⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7016110 | 0.89 | — | — | |
| SCHEMBL6893260 | 0.82 | — | — | |
| SCHEMBL6385097 | 0.81 | POLB (0.36) | — | |
| SCHEMBL7015218 | 0.81 | MEN1 (0.39) | — | |
| SCHEMBL27582780 | 0.81 | TSPO (0.37) | — | |
| SCHEMBL6386347 | 0.79 | MEN1 (0.39) | — | |
| SCHEMBL7017481 | 0.78 | KMT2A (0.40) | — | |
| SCHEMBL7018959 | 0.78 | MEN1 (0.43) | — | |
| SCHEMBL1624854 | 0.78 | FAAH (0.39) | — | |
| SCHEMBL27582837 | 0.77 | NR1H2 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1326864-A2 | ARYL OR HETEROARYL FUSED IMIDAZOLE COMPOUNDS AS ANTI-INFLAMMATORY AND ANALGESIC AGENTS | PFIZER PHARMACEUTICALS INC. (JP) | 2003-07-16 | — | — | EP | disclosed |
| WO-2002032900-A2 | ARYL OR HETEROARYL FUSED IMIDAZOLE COMPOUNDS AS ANTI-INFLAMMATORY AND ANALGESIC AGENTS | PFIZER PHARMACEUTICALS INC. (JP) | 2002-04-25 | — | — | WO | disclosed |