⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7016110 | 0.92 | — | — | |
| SCHEMBL1628195 | 0.86 | — | — | |
| SCHEMBL7017450 | 0.82 | — | — | |
| SCHEMBL1626266 | 0.81 | — | — | |
| SCHEMBL7018464 | 0.80 | — | — | |
| SCHEMBL1628190 | 0.79 | TP53 (0.40) | — | |
| SCHEMBL1628192 | 0.78 | P2RX3 (0.40) | — | |
| SCHEMBL5999775 | 0.76 | — | — | |
| SCHEMBL1624082 | 0.76 | AGTR1 (0.43) | — | |
| SCHEMBL1623504 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6710054-B2 | CONTAINING SULFONYLAMINOCARBONYL GROUPS; PROSTAGLANDIN INHIBITORS | PFIZER INC | 2004-03-23 | — | — | US | disclosed |
| US-20020107273-A1 | Aryl or heteroaryl fused imidazole compounds as anti-inflammatory and analgesic agents | ASKAT INC. (JP) | 2002-08-08 | — | — | US | disclosed |