Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | PRKCI | P41743 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2732575 | 0.72 | — | — | |
| SCHEMBL28051130 | 0.65 | SLC2A1 (0.33) | SLC2A1ALDH1A1PARP1PRKCIPDE4B | |
| SCHEMBL16416075 | 0.61 | SLC2A1 (0.36) | SLC2A1ALDH1A1PARP1PRKCIPDE4B | |
| SCHEMBL1009530 | 0.61 | DRD4 (0.42) | SLC2A1ALDH1A1PARP1PRKCIPDE4B | |
| SCHEMBL18822678 | 0.60 | DRD4 (0.41) | SLC2A1ALDH1A1PARP1PRKCIPDE4B | |
| SCHEMBL26703722 | 0.58 | PNMT (0.37) | SLC2A1PARP1 | |
| SCHEMBL14603877 | 0.57 | NOTUM (0.35) | SLC2A1ALDH1A1PARP1PRKCIPDE4B | |
| SCHEMBL17825573 | 0.56 | ALDH1A1 (0.39) | ALDH1A1PARP1 | |
| SCHEMBL7012459 | 0.56 | SLC2A1 (0.32) | SLC2A1ALDH1A1PARP1PRKCIPDE4B | |
| SCHEMBL4564464 | 0.55 | HSD17B10 (0.50) | SLC2A1ALDH1A1PARP1PRKCIPDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0733633-A1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-09-25 | — | — | EP | claimed |
| EP-0733633-B1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-05-28 | — | — | EP | disclosed |
| EP-0733633-A1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-09-25 | — | — | EP | disclosed |