Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 6/20 | 0.56 |
| ▸ | RAB9A | P51151 | 6/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | CES2 | O00748 | 1/20 | 0.56 |
| ▸ | CES1 | P23141 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.55 |
| ▸ | ACP3 | P15309 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.48 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6201289 | 0.93 | ALDH1A1 (0.61) | ALDH1A1CYP1A2L3MBTL1NPC1RAB9A | |
| SCHEMBL3089210 | 0.91 | ALDH1A1 (0.62) | ALDH1A1CYP1A2NPC1RAB9AMAPT | |
| SCHEMBL15092882 | 0.91 | ALDH1A1 (0.59) | ALDH1A1CYP1A2L3MBTL1NPC1RAB9A | |
| SCHEMBL15096860 | 0.91 | ALDH1A1 (0.59) | ALDH1A1CYP1A2L3MBTL1NPC1RAB9A | |
| SCHEMBL9157900 | 0.85 | ALDH1A1 (0.64) | ALDH1A1CYP1A2L3MBTL1NPC1RAB9A | |
| SCHEMBL3105019 | 0.85 | ALDH1A1 (0.55) | ALDH1A1CYP1A2L3MBTL1NPC1RAB9A | |
| SCHEMBL2150940 | 0.85 | ALDH1A1 (0.55) | ALDH1A1CYP1A2L3MBTL1NPC1RAB9A | |
| SCHEMBL6208904 | 0.85 | RAB9A (0.58) | ALDH1A1L3MBTL1NPC1RAB9AMAPT | |
| SCHEMBL6210392 | 0.85 | RAB9A (0.58) | ALDH1A1L3MBTL1NPC1RAB9AMAPT | |
| SCHEMBL6844006 | 0.84 | CYP1A2 (0.56) | ALDH1A1CYP1A2L3MBTL1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105801576-A | Synthetic method of indolizine compounds | 湖北科技学院 | 2016-07-27 | — | — | CN | claimed |
| CN-105801576-A | Synthetic method of indolizine compounds | 湖北科技学院 | 2016-07-27 | — | — | CN | disclosed |
| CN-101812002-A | Synthesizing process of 4-methoxy-alpha-[(3-methoxyphenyl)sulfo]-acetophenone | SHANDONG XINHUA PHARMACEUTICAL | 2010-08-25 | — | — | CN | disclosed |
| EP-0733633-B1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-05-28 | — | — | EP | disclosed |
| EP-0877024-B1 | SUBSTITUTED 6-H-1,3,4-THIADIAZINE-2-AMINES, THE USE THEREOF AS AN AESTHETISING, CARDIOVASCULAR AND HYPOMETABOLIC AGENTS, AND A PHARMACEUTICAL COMPOSITION CONTAINING THEM | N T PREDPR LIGAND OBSCHESTVO S (RU) | 2002-02-20 | — | — | EP | disclosed |
| US-6313111-B1 | ADMINISTERING TO PATIENT TO RETARD METABOLISM SO AS TO REDUCE BODY TEMPERATURE, OXYGEN INTAKE OR BOTH | THE PROCTER & GAMBLE COMPANY | 2001-11-06 | — | — | US | disclosed |
| EP-0877024-A1 | SUBSTITUTED 6-H-1,3,4-THIADIAZINE-2-AMINES, THE USE THEREOF AS AN AESTHETISING, CARDIOVASCULAR AND HYPOMETABOLIC AGENTS, AND A PHARMACEUTICAL COMPOSITION CONTAINING THEM | THE PROCTER & GAMBLE COMPANY (US) | 1998-11-11 | — | — | EP | disclosed |
| US-5753664-A | ANTITUMOR AGENTS, PYRIMIDONES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-05-19 | — | — | US | disclosed |
| EP-0733633-A1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-09-25 | — | — | EP | disclosed |