Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 3/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7015754 | 0.81 | CHRNA7 (0.54) | DRD2CHRNA7DRD3 | |
| Hydrochloric Acid SCHEMBL7015707 | 0.80 | CHRNA7 (0.52) | DRD2CHRNA7DRD3 | |
| SCHEMBL3261357 | 0.74 | CA2 (0.50) | CA12CA1CA2CA9 | |
| SCHEMBL7013326 | 0.71 | CNR1 (0.42) | MTNR1BCHRNA7 | |
| SCHEMBL875456 | 0.69 | CTNNB1 (0.51) | CA12CA1CA2CA9 | |
| SCHEMBL22411069 | 0.69 | MTNR1B (0.51) | MTNR1BDRD2DRD3 | |
| SCHEMBL2176489 | 0.68 | PRKCI (0.69) | CA12CA1CA2CA9 | |
| SCHEMBL29503137 | 0.68 | PRKCI (0.69) | CA12CA1CA2CA9 | |
| SCHEMBL9479673 | 0.67 | MAPT (0.52) | CA12CA1CA2CA9 | |
| SCHEMBL29010952 | 0.67 | CA12 (0.53) | CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1102769-B1 | TRICYCLIC CARBOXAMIDES | SMITHKLINE BEECHAM PLC (GB) | 2003-04-16 | — | — | EP | claimed |