Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7099787 | 0.80 | CHRNA7 (0.45) | CNR1CNR2MTNR1BCHRNA7 | |
| SCHEMBL7017829 | 0.75 | CHRM5 (0.42) | CNR1CNR2 | |
| SCHEMBL7555526 | 0.71 | CNR1 (0.51) | CNR1CNR2MTNR1BCHRNA7 | |
| SCHEMBL7017907 | 0.71 | HRH3 (0.39) | MTNR1BCHRNA7 | |
| SCHEMBL8218668 | 0.68 | NPC1 (0.59) | MTNR1BMEN1TSHRKMT2ACHRNA7 | |
| SCHEMBL7519048 | 0.67 | CHRNA7 (0.50) | CNR1CNR2CHRNA7 | |
| SCHEMBL15092129 | 0.67 | GRM5 (0.53) | GRM5MEN1KMT2AALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL8216489 | 0.67 | NPC1 (0.58) | MTNR1BMEN1TSHRKMT2ACHRNA7 | |
| SCHEMBL11904103 | 0.66 | GPR119 (0.55) | GPR119ACHEMAPT | |
| SCHEMBL6832862 | 0.66 | ALDH1A1 (0.56) | GRM5MEN1KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1102769-B1 | TRICYCLIC CARBOXAMIDES | SMITHKLINE BEECHAM PLC (GB) | 2003-04-16 | — | — | EP | claimed |