Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.38 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.37 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6300911 | 0.83 | DPP4 (0.58) | DPP4ALDH1A1KDM4EHSD17B10POLB | |
| SCHEMBL21750029 | 0.81 | DPP4 (0.56) | DPP4ALDH1A1KDM4EHSD17B10POLB | |
| SCHEMBL4499016 | 0.79 | TDP1 (0.41) | KDM4EPOLBKMT2AMEN1TDP1 | |
| SCHEMBL7015064 | 0.79 | DPP4 (0.48) | DPP4ALDH1A1KDM4EHSD17B10POLB | |
| SCHEMBL4638190 | 0.79 | ALDH1A1 (0.52) | DPP4ALDH1A1KDM4EHSD17B10CSNK2A2 | |
| SCHEMBL3574434 | 0.78 | DPP4 (0.47) | DPP4ALDH1A1KDM4EHSD17B10POLB | |
| SCHEMBL17774721 | 0.78 | CA12 (0.41) | ALDH1A1KDM4EHSD17B10POLBCSNK2A2 | |
| SCHEMBL2789527 | 0.78 | DPP4 (0.52) | DPP4ALDH1A1KDM4EHSD17B10CSNK2A2 | |
| SCHEMBL31335850 | 0.78 | DPP4 (0.52) | DPP4ALDH1A1KDM4EHSD17B10CSNK2A2 | |
| SCHEMBL29042676 | 0.78 | DPP4 (0.47) | DPP4ALDH1A1KDM4EHSD17B10POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003106435-A1 | FUSED-RING PYRIMIDIN-4(3H)-ONE DERIVATIVES, PROCESSES FOR THE PREPARATION AND USES THEREOF | SANKYO COMPANY, LIMITED (JP) | 2003-12-24 | — | — | WO | disclosed |