Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 17/20 | 0.43 |
| ▸ | PPARA | Q07869 | 5/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6730271 | 0.91 | ELANE (0.38) | PPARGPPARAITGB3ITGA2BELANE | |
| SCHEMBL7010549 | 0.81 | PPARG (0.51) | PPARGPPARAELANE | |
| SCHEMBL6221543 | 0.80 | PPARG (0.36) | PPARGPPARAITGB3ITGA2B | |
| SCHEMBL6222076 | 0.75 | LDHA (0.42) | PPARGITGB3ITGA2B | |
| SCHEMBL6284756 | 0.74 | NPR3 (0.33) | PPARGITGB3ITGA2BELANE | |
| SCHEMBL6289055 | 0.72 | ELANE (0.48) | PPARGPPARAELANE | |
| SCHEMBL6221383 | 0.71 | PPARG (0.45) | PPARGPPARA | |
| SCHEMBL6222298 | 0.71 | PDE3B (0.47) | PPARGITGB3ITGA2B | |
| SCHEMBL6221979 | 0.71 | ITGB1 (0.53) | PPARGPPARA | |
| SCHEMBL6222810 | 0.70 | PDE3B (0.46) | PPARGITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1282621-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | Aventis Pharma S.A. (FR) | 2003-02-12 | — | — | EP | disclosed |
| WO-2001085729-A1 | NOVEL VITRONECTIN RECEPTOR ANTAGONISTS | AVENTIS PHARMA S.A. (FR) | 2001-11-15 | — | — | WO | disclosed |