Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.59 |
| ▸ | PPARG | P37231 | 14/20 | 0.58 |
| ▸ | PPARD | Q03181 | 11/20 | 0.58 |
| ▸ | PPARA | Q07869 | 11/20 | 0.52 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2728563 | 0.85 | ITGB3 (0.69) | PPARGPPARDPPARAITGB3ITGA2B | |
| SCHEMBL5026508 | 0.85 | ITGB3 (0.69) | PPARGPPARDPPARAITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL6771655 | 0.84 | ITGB3 (0.68) | PPARGPPARDPPARAITGB3ITGA2B | |
| SCHEMBL5727671 | 0.84 | CYP1A2 (0.61) | PPARGPPARDPPARAITGB3ITGA2B | |
| SCHEMBL6484840 | 0.84 | PPARG (0.65) | LDHAPPARGPPARDPPARA | |
| SCHEMBL6379685 | 0.81 | PPARG (0.57) | LDHAPPARGPPARDPPARAFFAR1 | |
| SCHEMBL4653947 | 0.81 | PPARA (0.72) | PPARGPPARDPPARA | |
| SCHEMBL8823250 | 0.79 | ITGB3 (0.42) | LDHAPPARGPPARDPPARAITGB3 | |
| SCHEMBL7253399 | 0.79 | FFAR1 (0.71) | PPARGPPARDPPARAITGB3ITGA2B | |
| SCHEMBL6704879 | 0.79 | PPARG (0.71) | LDHAPPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1252150-B1 | HETEROCYCLIC DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SERVIER LAB (FR) | 2003-06-04 | — | — | EP | disclosed |
| EP-1252150-A1 | NOVEL HETEROCYCLIC DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | Les Laboratoires Servier (FR) | 2002-10-30 | — | — | EP | disclosed |
| WO-2001057002-A1 | NOVEL HETEROCYCLIC DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2001-08-09 | — | — | WO | disclosed |