Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 3/20 | 0.69 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.69 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.56 |
| ▸ | ACHE | P22303 | 1/20 | 0.56 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.56 |
| ▸ | DRD3 | P35462 | 1/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5026508 | 1.00 | ITGB3 (0.69) | ITGB3ITGA2BHIF1ACYP3A4ALOX15 | |
| Hydrochloric Acid SCHEMBL6771655 | 0.98 | ITGB3 (0.68) | ITGB3ITGA2BHIF1ACYP3A4ALOX15 | |
| SCHEMBL18526793 | 0.94 | ITGB3 (0.74) | ITGB3ITGA2BHIF1ACYP3A4ALOX15 | |
| SCHEMBL22442176 | 0.92 | ITGB3 (0.76) | ITGB3ITGA2BHIF1ACYP3A4ALOX15 | |
| SCHEMBL22442179 | 0.92 | ITGB3 (0.76) | ITGB3ITGA2BHIF1ACYP3A4ALOX15 | |
| SCHEMBL27654977 | 0.90 | ITGB3 (0.77) | ITGB3ITGA2BHIF1ACYP3A4ALOX15 | |
| SCHEMBL27674868 | 0.89 | ITGB3 (0.80) | ITGB3ITGA2BHIF1ACYP3A4ALOX15 | |
| SCHEMBL20400610 | 0.86 | ITGB3 (0.81) | ITGB3ITGA2BHIF1ACYP3A4ALOX15 | |
| SCHEMBL31369805 | 0.86 | ITGB3 (0.81) | ITGB3ITGA2BHIF1ACYP3A4ALOX15 | |
| SCHEMBL10181470 | 0.86 | ITGB3 (0.71) | ITGB3ITGA2BHIF1AALOX15PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12359192-B2 | Methods and compositions for display of macrocyclic peptides | UNIVERSITY OF ROCHESTER (US) | 2025-07-15 | — | — | US | claimed |
| US-20250197448-A1 | CYCLOPEPTIBODIES AND USES THEREOF | UNIVERSITY OF ROCHESTER (US) | 2025-06-19 | — | — | US | claimed |
| EP-4490202-A1 | CYCLOPEPTIBODIES AND USES THEREOF | University of Rochester (US) | 2025-01-15 | — | — | EP | claimed |
| WO-2023173084-A9 | CYCLOPEPTIBODIES AND USES THEREOF | UNIVERSITY OF ROCHESTER (US) | 2023-12-14 | — | — | WO | claimed |
| WO-2023173084-A1 | CYCLOPEPTIBODIES AND USES THEREOF | UNIVERSITY OF ROCHESTER (US) | 2023-09-14 | — | — | WO | claimed |
| EP-3087088-B1 | METHODS AND COMPOSITIONS FOR RIBOSOMAL SYNTHESIS OF MACROCYCLIC PEPTIDES | UNIV ROCHESTER (US) | 2022-05-25 | — | — | EP | claimed |
| US-20200299675-A1 | Methods and Compositions for Display of Macrocyclic Peptides | UNIVERSITY OF ROCHESTER | 2020-09-24 | — | — | US | claimed |
| US-10544191-B2 | Methods and compositions for ribosomal synthesis of macrocyclic peptides | UNIVERSITY OF ROCHESTER (US) | 2020-01-28 | — | — | US | claimed |
| US-20160355552-A1 | METHODS AND COMPOSITIONS FOR RIBOSOMAL SYNTHESIS OF MACROCYCLIC PEPTIDES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-12-08 | — | — | US | claimed |
| EP-3087088-A2 | METHODS AND COMPOSITIONS FOR RIBOSOMAL SYNTHESIS OF MACROCYCLIC PEPTIDES | University Of Rochester (US) | 2016-11-02 | — | — | EP | claimed |
| WO-2015100277-A9 | METHODS AND COMPOSITIONS FOR RIBOSOMAL SYNTHESIS OF MACROCYCLIC PEPTIDES | UNIVERSITY OF ROCHESTER (US) | 2015-10-01 | — | — | WO | claimed |
| WO-2015100277-A2 | METHODS AND COMPOSITIONS FOR RIBOSOMAL SYNTHESIS OF MACROCYCLIC PEPTIDES | UNIVERSITY OF ROCHESTER (US) | 2015-07-02 | — | — | WO | claimed |
| US-6833382-B2 | By muta-synthesis using a mutated micro-organism to influence the biosynthesis of at least one of the precursors of group B streptogramines; mutant strain employed is preferably derived from the strain S. pristinaespiralis SP92 | AVENTIS PHARMA S.A. (FR) | 2004-12-21 | — | — | US | claimed |
| US-20020142947-A1 | STREPTOGRAMINS AND METHOD FOR PREPARING SAME BY MUTASYNTHESIS | AVENTIS PHARMA, S.A. | 2002-10-03 | — | — | US | claimed |
| CN-1152338-A | Streptogramines and method for preparing same by mutasynthesis | RHONE POULENC RORER SA (FR) | 1997-06-18 | — | — | CN | claimed |
| EP-0770132-A1 | STREPTOGRAMINES AND METHOD FOR PREPARING SAME BY MUTASYNTHESIS | Aventis Pharma S.A. (FR) | 1997-05-02 | — | — | EP | claimed |
| WO-1996001901-A1 | STREPTOGRAMINES AND METHOD FOR PREPARING SAME BY MUTASYNTHESIS | RHONE-POULENC RORER S.A. (FR) | 1996-01-25 | — | — | WO | claimed |
| US-12359192-B2 | Methods and compositions for display of macrocyclic peptides | UNIVERSITY OF ROCHESTER (US) | 2025-07-15 | — | — | US | disclosed |
| EP-0770132-A1 | STREPTOGRAMINES AND METHOD FOR PREPARING SAME BY MUTASYNTHESIS | Aventis Pharma S.A. (FR) | 1997-05-02 | — | — | EP | disclosed |
| WO-1996001901-A1 | STREPTOGRAMINES AND METHOD FOR PREPARING SAME BY MUTASYNTHESIS | RHONE-POULENC RORER S.A. (FR) | 1996-01-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12359192-B2 | Methods and compositions for display of macrocyclic peptides | NGLY1, MICA, MRPL21 | ITGB3 3200/4885ITGA2B 3509/4885HIF1A 4443/4885 |
| US-10544191-B2 | Methods and compositions for ribosomal synthesis of macrocyclic peptides | MRPS27, MRPL21, RPLP2 | ITGB3 4814/4885ITGA2B 4821/4885HIF1A 4371/4885 |
| US-20250197448-A1 | CYCLOPEPTIBODIES AND USES THEREOF | FCGR3B, FCGRT, FCGR2A | ITGB3 3171/4885ITGA2B 2815/4885HIF1A 4369/4885 |
| US-20160355552-A1 | METHODS AND COMPOSITIONS FOR RIBOSOMAL SYNTHESIS OF MACROCYCLIC PEPTIDES | MRPS27, MRPL21, RPLP2 | ITGB3 4814/4885ITGA2B 4821/4885HIF1A 4371/4885 |
| US-20020142947-A1 | STREPTOGRAMINS AND METHOD FOR PREPARING SAME BY MUTASYNTHESIS | EMG1, FBL, SMS | ITGB3 4878/4885ITGA2B 4267/4885HIF1A 1689/4885 |
| US-20200299675-A1 | Methods and Compositions for Display of Macrocyclic Peptides | SPOUT1, NGLY1, VIP | ITGB3 3731/4885ITGA2B 3757/4885HIF1A 4562/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.