Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 3/20 | 0.51 |
| ▸ | DBF4 | Q9UBU7 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | MMP14 | P50281 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4506134 | 0.84 | KDM4E (0.57) | CDC7DBF4KDM4EKMT2AMAPT | |
| SCHEMBL7017749 | 0.80 | CDC7 (0.46) | CDC7DBF4KDM4EKMT2AMAPT | |
| SCHEMBL20838888 | 0.79 | DHODH (0.45) | KDM4EKMT2AMAPTMEN1NPC1 | |
| SCHEMBL7007577 | 0.76 | ALDH1A1 (0.49) | KDM4EKMT2AMAPTALDH1A1RXFP1 | |
| SCHEMBL20838921 | 0.76 | KMT2A (0.52) | CDC7DBF4KDM4EKMT2AMAPT | |
| SCHEMBL7199531 | 0.75 | RXFP1 (0.52) | KDM4EKMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL20838900 | 0.74 | KMT2A (0.54) | CDC7DBF4KDM4EKMT2AMAPT | |
| SCHEMBL7013488 | 0.74 | ALDH1A1 (0.55) | CDC7DBF4KDM4EKMT2AMAPT | |
| SCHEMBL27597665 | 0.72 | MAPT (0.61) | CDC7DBF4KDM4EKMT2AMAPT | |
| SCHEMBL4524894 | 0.71 | KMT2A (0.63) | CDC7DBF4KDM4EKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329454-A1 | THIENOPYRIMIDINE COMPOUNDS AND THEIR SALTS AND PROCESS FOR PREPARATION OF BOTH | NIPPON SODA CO., LTD. (JP) | 2003-07-23 | — | — | EP | disclosed |