Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 6/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | HTR2B | P41595 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.60 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.58 |
| ▸ | DRD2 | P14416 | 2/20 | 0.55 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.53 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.51 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.50 |
| ▸ | CTSK | P43235 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrahydroharman SCHEMBL21012020 | 1.00 | HTR7 (0.65) | HTR7CYP3A4CYP2D6CYP2C19MAPT | |
| Tetrahydroharman SCHEMBL29630308 | 1.00 | HTR7 (0.65) | HTR7CYP3A4CYP2D6CYP2C19MAPT | |
| Tetrahydroharman SCHEMBL29630296 | 1.00 | HTR7 (0.65) | HTR7CYP3A4CYP2D6CYP2C19MAPT | |
| SCHEMBL24428198 | 0.90 | BRD3 (0.55) | HTR7CYP3A4CYP2D6CYP2C19MAPT | |
| Tetrahydroharman SCHEMBL28697145 | 0.83 | MAPT (0.48) | HTR7CYP3A4CYP2D6CYP2C19MAPT | |
| SCHEMBL17839824 | 0.80 | HTR7 (0.65) | HTR7CYP3A4CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL9956719 | 0.80 | HTR7 (0.65) | HTR7CYP3A4CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL968830 | 0.80 | HTR7 (0.65) | HTR7CYP3A4CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL12212162 | 0.80 | HTR7 (0.65) | HTR7CYP3A4CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL21326157 | 0.80 | HTR7 (0.60) | HTR7CYP3A4CYP2D6CYP2C19MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115508484-B | Separation analysis method for chloroindole hydrazide chiral isomer | 山东京博农化科技股份有限公司 | 2025-04-25 | — | — | CN | claimed |
| CN-117694354-A | New application and method for promoting crop fruit color conversion by tetrahydrobeta carboline derivative | 山东京博农化科技股份有限公司 | 2024-03-15 | — | — | CN | claimed |
| CN-110759911-B | Carboline derivative, preparation method thereof and application thereof in preventing and treating plant viruses, killing bacteria and killing insects | 南开大学 | 2022-05-24 | — | — | CN | claimed |
| EP-3459950-B1 | TETRAHYDRO-BETA-CARBOLINE ALKALOID DERIVATIVES, METHOD FOR PREPARING THE SAME AND USE IN ASPECTS OF PREVENTING AND TREATING PLANT VIRUSES, AS FUNGICIDES AND INSECTICIDES | JINGBO AGROCHEMICALS TECH CO LTD (CN) | 2022-05-18 | — | — | EP | claimed |
| CN-104838254-A | Marking of material, marked material and process of authentication or dilution determination | SICPA HOLDING SA | 2015-08-12 | — | — | CN | claimed |
| US-12630512-B2 | Agents for differentiating stem cells and treating cancer | MINERVA BIOTECHNOLOGIES CORPORATION (US) | 2026-05-19 | — | — | US | disclosed |
| CN-117694354-B | New application and method for promoting crop fruit color conversion by tetrahydrobeta carboline derivative | 山东京博农化科技股份有限公司 | 2026-04-21 | — | — | CN | disclosed |
| US-20260014180-A1 | BIOACTIVES AND THEIR USES | AREPA IP LTD (NZ) | 2026-01-15 | — | — | US | disclosed |
| EP-3600451-B1 | AGENTS FOR DIFFERENTIATING STEM CELLS AND TREATING CANCER | MINERVA BIOTECHNOLOGIES CORP (US) | 2025-12-24 | — | — | EP | disclosed |
| CN-115508484-B | Separation analysis method for chloroindole hydrazide chiral isomer | 山东京博农化科技股份有限公司 | 2025-04-25 | — | — | CN | disclosed |
| CN-115508484-B | Separation analysis method for chloroindole hydrazide chiral isomer | 山东京博农化科技股份有限公司 | 2025-04-25 | — | — | CN | disclosed |
| US-20250090564-A1 | BIOACTIVES AND THEIR USES | AREPA IP LIMITED (NZ) | 2025-03-20 | — | — | US | disclosed |
| EP-0705832-B1 | Serotonergic modulators | LILLY CO ELI (GB) | 2003-08-13 | — | — | EP | disclosed |
| CN-1045602-C | Pharmaceutical compounds | LILLY INDUSTRIES LTD (GB) | 1999-10-13 | — | — | CN | disclosed |
| US-5965582-A | ANTIHISTAMINES | ASTA MEDICA AKTIENGESELLSCHAFT (DE) | 1999-10-12 | — | — | US | disclosed |
| US-5563147-A | CENTRAL NERVOUS SYSTEM DISORDERS | ELI LILLY AND COMPANY (US) | 1996-10-08 | — | — | US | disclosed |
| CN-1129219-A | Pharmaceutical compounds | LILLY INDUSTRIES LTD (GB) | 1996-08-21 | — | — | CN | disclosed |
| EP-0705832-A1 | Serotonergic modulators | LILLY INDUSTRIES LIMITED (GB) | 1996-04-10 | — | — | EP | disclosed |
| US-5169852-A | Anorexigenic agents | NEUREX CORPORATION (US) | 1992-12-08 | — | — | US | disclosed |
| US-4565870-A | Process for the preparation of a salt of 1-(γ-halopropyl)-1,2,3,4-β-carbolines | BASF AKTIENGESELLSCHAFT (DE) | 1986-01-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250090564-A1 | BIOACTIVES AND THEIR USES | MAOA, MAOB, TYR | HTR7 176/4885CYP3A4 100/4885CYP2D6 78/4885 |
| US-20260014180-A1 | BIOACTIVES AND THEIR USES | MAOB, MAOA, COMT | HTR7 29/4885CYP3A4 33/4885CYP2D6 61/4885 |
| US-12630512-B2 | Agents for differentiating stem cells and treating cancer | MCL1, POU2F1, NES | HTR7 2402/4885CYP3A4 3258/4885CYP2D6 3225/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.