Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 7/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.45 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrahydroharman SCHEMBL7018798 | 0.83 | HTR7 (0.65) | MAPTALDH1A1KDM4EHTR2BPSMD14 | |
| Tetrahydroharman SCHEMBL29630308 | 0.83 | HTR7 (0.65) | MAPTALDH1A1KDM4EHTR2BPSMD14 | |
| Tetrahydroharman SCHEMBL29630296 | 0.83 | HTR7 (0.65) | MAPTALDH1A1KDM4EHTR2BPSMD14 | |
| Tetrahydroharman SCHEMBL21012020 | 0.83 | HTR7 (0.65) | MAPTALDH1A1KDM4EHTR2BPSMD14 | |
| SCHEMBL24428198 | 0.75 | BRD3 (0.55) | MAPTALDH1A1KDM4EHTR2BPSMD14 | |
| SCHEMBL8322968 | 0.71 | GRIN2B (0.70) | MAPKAPK2HTR7CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL21883968 | 0.71 | GRIN2B (0.70) | MAPKAPK2HTR7CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL29756361 | 0.71 | GRIN2B (0.70) | MAPKAPK2HTR7CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL273473 | 0.71 | MAPKAPK2 (0.67) | ALDH1A1KDM4EMAPKAPK2HTR7CYP3A4 | |
| SCHEMBL10481507 | 0.71 | MAPKAPK2 (0.67) | ALDH1A1KDM4EMAPKAPK2HTR7CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114057738-A | Synthesis method of chloroindole hydrazide | 京博农化科技有限公司 | 2022-02-18 | — | — | CN | disclosed |