Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G10 | O15496 | 9/20 | 0.35 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.32 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.31 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.30 |
| ▸ | MGLL | Q99685 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1626307 | 0.85 | MEN1 (0.39) | SMN1; SMN2MEN1KMT2ACYP4F2CYP4A11 | |
| SCHEMBL3949910 | 0.72 | MEN1 (0.38) | SMN1; SMN2MEN1KMT2APOLBPABPC1 | |
| SCHEMBL1623477 | 0.69 | GPR4 (0.43) | — | |
| SCHEMBL1625960 | 0.68 | FAAH (0.40) | MAPTMEN1KMT2APOLBPABPC1 | |
| SCHEMBL1624749 | 0.68 | MEN1 (0.37) | MEN1KMT2A | |
| SCHEMBL1624736 | 0.67 | PTGER4 (0.57) | MAPTMEN1KMT2ACYP4F2CYP4A11 | |
| SCHEMBL30513699 | 0.67 | PTGER4 (0.57) | MAPTMEN1KMT2ACYP4F2CYP4A11 | |
| SCHEMBL1625832 | 0.66 | TSHR (0.36) | MAPTSMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL1625262 | 0.65 | PPARG (0.42) | MAPTTLR8MEN1KMT2ANR1H2 | |
| SCHEMBL1624649 | 0.64 | MEN1 (0.43) | MAPTMEN1KMT2ACYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1326864-A2 | ARYL OR HETEROARYL FUSED IMIDAZOLE COMPOUNDS AS ANTI-INFLAMMATORY AND ANALGESIC AGENTS | PFIZER PHARMACEUTICALS INC. (JP) | 2003-07-16 | — | — | EP | disclosed |
| WO-2002032900-A2 | ARYL OR HETEROARYL FUSED IMIDAZOLE COMPOUNDS AS ANTI-INFLAMMATORY AND ANALGESIC AGENTS | PFIZER PHARMACEUTICALS INC. (JP) | 2002-04-25 | — | — | WO | disclosed |