Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.36 |
| ▸ | OGA | O60502 | 8/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL701908 | 1.00 | KDM4E (0.37) | KDM4EMEN1HTTKMT2AKCNA5 | |
| SCHEMBL702257 | 0.87 | SETD1B (0.33) | OGANTRK1FLT3 | |
| SCHEMBL702258 | 0.87 | SETD1B (0.33) | OGANTRK1FLT3 | |
| SCHEMBL702580 | 0.87 | OGA (0.39) | KDM4EMEN1HTTKMT2AOGA | |
| SCHEMBL702579 | 0.87 | OGA (0.39) | KDM4EMEN1HTTKMT2AOGA | |
| SCHEMBL708508 | 0.81 | UTS2R (0.32) | — | |
| SCHEMBL651200 | 0.78 | HPGD (0.43) | KDM4EMEN1HTTKMT2AKCNA5 | |
| SCHEMBL651201 | 0.78 | HPGD (0.43) | KDM4EMEN1HTTKMT2AKCNA5 | |
| SCHEMBL705496 | 0.78 | PIK3CA (0.37) | PARP1 | |
| SCHEMBL705497 | 0.78 | PIK3CA (0.37) | PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2423204-A1 | THIAZOLIDINONE DERIVATIVE | SBI Biotech Co., Ltd. (JP) | 2012-02-29 | — | — | EP | disclosed |