Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SETD1B | Q9UPS6 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 2/20 | 0.33 |
| ▸ | OGA | O60502 | 7/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.31 |
| ▸ | CSF1R | P07333 | 1/20 | 0.31 |
| ▸ | FLT3 | P36888 | 1/20 | 0.31 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.31 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.31 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.31 |
| ▸ | USP7 | Q93009 | 1/20 | 0.31 |
| ▸ | USP47 | Q96K76 | 1/20 | 0.31 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL702258 | 1.00 | SETD1B (0.33) | SETD1BAURKAOGANTRK1CSF1R | |
| SCHEMBL708508 | 0.92 | UTS2R (0.32) | SETD1BAURKA | |
| SCHEMBL702580 | 0.88 | OGA (0.39) | OGA | |
| SCHEMBL702579 | 0.88 | OGA (0.39) | OGA | |
| SCHEMBL701908 | 0.87 | KDM4E (0.37) | OGANTRK1FLT3 | |
| SCHEMBL701907 | 0.87 | KDM4E (0.37) | OGANTRK1FLT3 | |
| SCHEMBL703954 | 0.86 | PIK3CA (0.32) | — | |
| SCHEMBL703955 | 0.86 | PIK3CA (0.32) | — | |
| SCHEMBL705497 | 0.83 | PIK3CA (0.37) | — | |
| SCHEMBL705496 | 0.83 | PIK3CA (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2423204-A1 | THIAZOLIDINONE DERIVATIVE | SBI Biotech Co., Ltd. (JP) | 2012-02-29 | — | — | EP | disclosed |