Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.39 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7028611 | 0.82 | TDP1 (0.42) | CNR1CNR2KDM4EALDH1A1LMNA | |
| SCHEMBL10783351 | 0.77 | LMNA (0.47) | CNR1CNR2CYP2A13AKR1C3KDM4E | |
| SCHEMBL17240230 | 0.77 | CNR1 (0.47) | CNR1CNR2CYP2A13AKR1C3KDM4E | |
| SCHEMBL15797508 | 0.74 | CNR1 (0.51) | CNR1CNR2CYP2A13AKR1C3KDM4E | |
| SCHEMBL15797510 | 0.73 | DPP4 (0.71) | CNR1CNR2CYP2A13AKR1C3KDM4E | |
| SCHEMBL18274467 | 0.73 | ALDH1A1 (0.64) | CNR1CNR2CYP2A13AKR1C3KDM4E | |
| SCHEMBL14968308 | 0.72 | ESR1 (0.45) | CNR1CNR2MEN1KMT2AALDH1A1 | |
| SCHEMBL6997279 | 0.70 | PRKDC (0.58) | KDM4EMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL20772277 | 0.69 | PRKDC (0.47) | KDM4EMEN1KMT2AALDH1A1TP53 | |
| SCHEMBL1516145 | 0.68 | ALDH1A1 (0.50) | ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1317433-A2 | INHIBITORS OF GLYCOGEN SYNTHASE KINASE 3 | CHIRON CORPORATION (US) | 2003-06-11 | — | — | EP | disclosed |
| WO-2002020495-A2 | INHIBITORS OF GLYCOGEN SYNTHASE KINASE 3 | CHIRON CORPORATION (US) | 2002-03-14 | — | — | WO | disclosed |