Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 4/20 | 0.54 |
| ▸ | GABRD | O14764 | 4/20 | 0.54 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.54 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.54 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.54 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.54 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.54 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.54 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.54 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.54 |
| ▸ | GABRA4 | P48169 | 4/20 | 0.54 |
| ▸ | GABRE | P78334 | 4/20 | 0.54 |
| ▸ | GABRA6 | Q16445 | 4/20 | 0.54 |
| ▸ | GABRG1 | Q8N1C3 | 4/20 | 0.54 |
| ▸ | GABRG3 | Q99928 | 4/20 | 0.54 |
| ▸ | GABRQ | Q9UN88 | 4/20 | 0.54 |
| ▸ | DDT | P30046 | 1/20 | 0.51 |
| ▸ | LDHA | P00338 | 1/20 | 0.49 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.48 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL686861 | 0.81 | DDT (0.74) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL29914342 | 0.81 | DDT (0.74) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL28109275 | 0.79 | LDHA (0.57) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL27541520 | 0.79 | DDT (0.51) | DDTLDHAMEN1ALDH1A1GAA | |
| SCHEMBL451330 | 0.77 | MAPT (0.55) | MEN1ALDH1A1GAAHPGDKMT2A | |
| SCHEMBL31377031 | 0.77 | MAPT (0.55) | MEN1ALDH1A1GAAHPGDKMT2A | |
| SCHEMBL28675025 | 0.76 | GAA (0.54) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7276328 | 0.76 | DDT (0.48) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Hydrochloric Acid SCHEMBL6775126 | 0.75 | MAPT (0.53) | MEN1ALDH1A1GAAHPGDKMT2A | |
| SCHEMBL667582 | 0.75 | PTPN1 (0.59) | ALDH1A1PTPN1HNF4AAKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670525-A | Substituted 4-phenyl-6-amino-nicotinic acid compounds useful in the treatment of CNS disorders | BAYER AKTIENGESELLSCHAFT (DE) | 1997-09-23 | — | — | US | claimed |
| CN-1127114-A | Use of substituted 4-phenyl-6-amino-nicotinic acid derivatives as medicaments | BAYER AG (DE) | 1996-07-24 | — | — | CN | claimed |
| US-20030232860-A1 | Medicine comprising dicyanopyridine derivative | ASTELLAS PHARMA INC. (JP) | 2003-12-18 | — | — | US | disclosed |
| CN-1441783-A | Drug containing dicyanopyridine derivative | YAMANOUCHI PHARMA CO LTD (JP) | 2003-09-10 | — | — | CN | disclosed |
| EP-1302463-A1 | MEDICINE COMPRISING DICYANOPYRIDINE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 2003-04-16 | — | — | EP | disclosed |
| US-5670525-A | Substituted 4-phenyl-6-amino-nicotinic acid compounds useful in the treatment of CNS disorders | BAYER AKTIENGESELLSCHAFT (DE) | 1997-09-23 | — | — | US | disclosed |
| US-5670525-A | Substituted 4-phenyl-6-amino-nicotinic acid compounds useful in the treatment of CNS disorders | BAYER AKTIENGESELLSCHAFT (DE) | 1997-09-23 | — | — | US | disclosed |
| US-5670525-A | Substituted 4-phenyl-6-amino-nicotinic acid compounds useful in the treatment of CNS disorders | BAYER AKTIENGESELLSCHAFT (DE) | 1997-09-23 | — | — | US | disclosed |
| CN-1127114-A | Use of substituted 4-phenyl-6-amino-nicotinic acid derivatives as medicaments | BAYER AG (DE) | 1996-07-24 | — | — | CN | disclosed |
| CN-1127114-A | Use of substituted 4-phenyl-6-amino-nicotinic acid derivatives as medicaments | BAYER AG (DE) | 1996-07-24 | — | — | CN | disclosed |
| CN-1127114-A | Use of substituted 4-phenyl-6-amino-nicotinic acid derivatives as medicaments | BAYER AG (DE) | 1996-07-24 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030232860-A1 | Medicine comprising dicyanopyridine derivative | KCNN3, KCNN2, KCNN1 | GABRP 879/4885GABRD 538/4885GABRA1 1045/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.