Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.39 |
| ▸ | SOAT1 | P35610 | 3/20 | 0.39 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.39 |
| ▸ | SQOR | Q9Y6N5 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7018816 | 0.89 | ALDH1A1 (0.48) | ALDH1A1MAPK1HSD17B10ADORA1ADORA2A | |
| SCHEMBL7018766 | 0.88 | CYP1A2 (0.45) | ALDH1A1MAPK1HSD17B10ADORA1ADORA2A | |
| SCHEMBL7012893 | 0.86 | RAB9A (0.44) | ALDH1A1MAPK1HSD17B10ADORA1ADORA2A | |
| SCHEMBL7020733 | 0.86 | ALDH1A1 (0.45) | ALDH1A1MAPK1HSD17B10ADORA1ADORA2A | |
| SCHEMBL7019913 | 0.84 | MAPK8 (0.45) | ALDH1A1MAPK1HSD17B10ADORA1ADORA3 | |
| SCHEMBL7021979 | 0.84 | ALDH1A1 (0.44) | ALDH1A1MAPK1HSD17B10ADORA1ADORA2A | |
| SCHEMBL7015455 | 0.84 | ALDH1A1 (0.46) | ALDH1A1MAPK1HSD17B10ADORA1ADORA2A | |
| SCHEMBL7025494 | 0.83 | NPC1 (0.46) | ALDH1A1MAPK1HSD17B10TSHRSMN1; SMN2 | |
| SCHEMBL7011446 | 0.82 | ALDH1A1 (0.44) | ALDH1A1MAPK1HSD17B10ADORA1SMN1; SMN2 | |
| SCHEMBL7015638 | 0.81 | ALDH1A1 (0.41) | ALDH1A1MAPK1HSD17B10ADORA1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030232860-A1 | Medicine comprising dicyanopyridine derivative | ASTELLAS PHARMA INC. (JP) | 2003-12-18 | — | — | US | disclosed |
| CN-1441783-A | Drug containing dicyanopyridine derivative | YAMANOUCHI PHARMA CO LTD (JP) | 2003-09-10 | — | — | CN | disclosed |
| EP-1302463-A1 | MEDICINE COMPRISING DICYANOPYRIDINE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 2003-04-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030232860-A1 | Medicine comprising dicyanopyridine derivative | KCNN3, KCNN2, KCNN1 | ALDH1A1 3292/4885MAPK1 2493/4885HSD17B10 3642/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.