Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 4/20 | 0.33 |
| ▸ | CA1 | P00915 | 4/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9159552 | 0.90 | TSHR (0.34) | — | |
| SCHEMBL7019571 | 0.88 | ACE2 (0.36) | ACE2CA2CA1MAPK1SLC15A1 | |
| SCHEMBL28716932 | 0.78 | ACE2 (0.47) | ACE2CA2CA1MAPK1SLC15A1 | |
| SCHEMBL8434330 | 0.77 | CA2 (0.37) | ACE2CA2CA1MAPK1SLC15A1 | |
| SCHEMBL9160867 | 0.76 | CA1 (0.40) | ACE2CA2CA1MAPK1SLC15A1 | |
| SCHEMBL28512178 | 0.75 | CA2 (0.36) | ACE2CA2CA1MAPK1SLC15A1 | |
| SCHEMBL4514707 | 0.74 | ACE2 (0.44) | ACE2CA2CA1MAPK1SLC15A1 | |
| Phosphonic Acid SCHEMBL7917448 | 0.73 | ACE2 (0.50) | ACE2CA2CA1MAPK1SLC15A1 | |
| SCHEMBL7614751 | 0.73 | KMT2A (0.45) | — | |
| SCHEMBL11915918 | 0.72 | ACE2 (0.42) | ACE2CA2CA1MAPK1SLC15A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0789022-B1 | Difluoroprostacyclins, intermediates for production thereof and processes for production thereof | ASAHI GLASS CO LTD (JP) | 2003-06-18 | — | — | EP | disclosed |
| EP-0669329-B1 | Difluorprostacyclins, intermediates for production thereof and processes for production thereof | ASAHI GLASS CO LTD (JP) | 1998-05-20 | — | — | EP | disclosed |
| US-5747531-A | STABILITY; ANTICOAGULANTS, VASODILATORS | ASAHI GLASS COMPANY LTD. (JP) | 1998-05-05 | — | — | US | disclosed |
| EP-0789022-A1 | Difluoroprostacyclins, intermediates for production thereof and process for production | ASAHI GLASS COMPANY LTD. (JP) | 1997-08-13 | — | — | EP | disclosed |
| US-5616732-A | Intermediates for difluoroprostacyclins and methods for their production | ASAHI GLASS COMPANY LTD. (JP) | 1997-04-01 | — | — | US | disclosed |
| US-5538995-A | Difluoroprostacyclins | ASAHI GLASS COMPANY LTD. (JP) | 1996-07-23 | — | — | US | disclosed |
| EP-0669329-A1 | Difluorprostacyclins, intermediates for production thereof and processes for production thereof | ASAHI GLASS COMPANY LTD. (JP) | 1995-08-30 | — | — | EP | disclosed |