Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.40 |
| ▸ | FDPS | P14324 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 6/20 | 0.34 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9463468 | 0.87 | CA1 (0.41) | CA1FDPSCA2ACE2MAPK1 | |
| SCHEMBL10644887 | 0.81 | MAPT (0.42) | CA1CA2MAPK1CYP3A4TSHR | |
| SCHEMBL8108999 | 0.81 | MAPT (0.42) | CA1CA2MAPK1CYP3A4TSHR | |
| SCHEMBL11374325 | 0.79 | ALDH1A1 (0.35) | CYP3A4TDP1LMNA | |
| SCHEMBL11308203 | 0.77 | CA2 (0.34) | CA1CA2MAPK1 | |
| SCHEMBL28427879 | 0.77 | GRIK1 (0.36) | — | |
| SCHEMBL7019573 | 0.76 | ACE2 (0.35) | CA1CA2ACE2MAPK1SLC15A1 | |
| SCHEMBL11437311 | 0.75 | FDPS (0.47) | CA1FDPS | |
| SCHEMBL28427864 | 0.75 | LTB4R (0.44) | TSHRLMNA | |
| SCHEMBL428739 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5380709-A | Prostaglandins E and anti ulcers containing same | K.K. UENO SEIYAKU OYO KENKYUJO (JP) | 1995-01-10 | — | — | US | disclosed |
| US-5225439-A | Side effect reduction | K.K. UENO SEIYAKU OYO KENKYUJO (JP) | 1993-07-06 | — | — | US | disclosed |