Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.39 |
| ▸ | SQOR | Q9Y6N5 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KISS1R | Q969F8 | 4/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7018766 | 0.90 | CYP1A2 (0.45) | ALDH1A1HSD17B10MAPK1MAPTHTT | |
| SCHEMBL7020733 | 0.90 | ALDH1A1 (0.45) | ALDH1A1HSD17B10MAPK1MAPTHTT | |
| SCHEMBL7018816 | 0.89 | ALDH1A1 (0.48) | ALDH1A1HSD17B10MAPK1MAPTKDM4E | |
| SCHEMBL7019274 | 0.88 | ALDH1A1 (0.47) | ALDH1A1HSD17B10MAPK1HPGDRAB9A | |
| SCHEMBL7012893 | 0.88 | RAB9A (0.44) | ALDH1A1HSD17B10MAPK1MAPTHTT | |
| SCHEMBL7021979 | 0.86 | ALDH1A1 (0.44) | ALDH1A1HSD17B10MAPK1MAPTKDM4E | |
| SCHEMBL7019913 | 0.86 | MAPK8 (0.45) | ALDH1A1HSD17B10MAPK1MAPTHTT | |
| SCHEMBL7015455 | 0.85 | ALDH1A1 (0.46) | ALDH1A1HSD17B10MAPK1MAPTHTT | |
| SCHEMBL7020448 | 0.85 | ALDH1A1 (0.43) | ALDH1A1HSD17B10MAPK1MAPTHPGD | |
| SCHEMBL7025494 | 0.84 | NPC1 (0.46) | ALDH1A1HSD17B10MAPK1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1302463-A1 | MEDICINE COMPRISING DICYANOPYRIDINE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 2003-04-16 | — | — | EP | disclosed |