Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 8/20 | 0.41 |
| ▸ | DRD2 | P14416 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1413322 | 0.90 | HTR6 (0.37) | HTR6 | |
| SCHEMBL7710645 | 0.84 | DRD2 (0.54) | HTR6DRD2HTR2A | |
| SCHEMBL6642794 | 0.82 | DRD2 (0.43) | HTR6DRD2HTR2ASLC6A4 | |
| SCHEMBL12127481 | 0.82 | HTR1B (0.46) | HTR6DRD2SLC6A4 | |
| SCHEMBL12127438 | 0.82 | DRD2 (0.39) | HTR6DRD2SLC6A4 | |
| SCHEMBL12128123 | 0.81 | APP (0.46) | HTR6DRD2SLC6A4 | |
| SCHEMBL12128118 | 0.80 | APP (0.46) | HTR6DRD2 | |
| SCHEMBL8182800 | 0.79 | DRD2 (0.41) | HTR6DRD2HTR2ASLC6A4 | |
| SCHEMBL7016909 | 0.78 | DRD2 (0.53) | HTR6DRD2HTR2ASLC6A4 | |
| SCHEMBL12127930 | 0.78 | EED (0.39) | HTR6DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1089993-B1 | 5-HT1F AGONISTS | LILLY CO ELI (US) | 2003-10-22 | — | — | EP | disclosed |