Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7015306 | 0.83 | FPR2 (0.46) | L3MBTL1MAOBMAPTNPSR1MAOA | |
| Hydrochloric Acid SCHEMBL7016531 | 0.82 | ALDH1A1 (0.42) | L3MBTL1RAB9AALDH1A1MAPTMEN1 | |
| SCHEMBL27431416 | 0.76 | RAB9A (0.51) | L3MBTL1HTR2AHTTRAB9AALDH1A1 | |
| SCHEMBL8247254 | 0.72 | HTR2A (0.60) | L3MBTL1HTR2AMAOBHTTRAB9A | |
| SCHEMBL27787156 | 0.71 | MAPT (0.56) | L3MBTL1HTR2AMAOBHTTRAB9A | |
| SCHEMBL29171050 | 0.70 | HTR2A (0.59) | L3MBTL1HTR2AMAOBHTTRAB9A | |
| SCHEMBL9091584 | 0.70 | BCL9 (0.44) | HTR2ARAB9AALDH1A1MAPTMEN1 | |
| SCHEMBL9782567 | 0.70 | IDO1 (0.56) | HTR2AMAOBHTTRAB9AALDH1A1 | |
| SCHEMBL9820376 | 0.70 | IDO1 (0.56) | HTR2AMAOBHTTRAB9AALDH1A1 | |
| SCHEMBL11098324 | 0.69 | HTR2A (0.58) | L3MBTL1HTR2AMAOBHTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0972769-B1 | NOVEL AMIDE DERIVATIVES AND MEDICINAL COMPOSITIONS THEREOF | YAMANOUCHI PHARMA CO LTD (JP) | 2003-04-16 | — | — | EP | disclosed |
| US-6177454-B1 | ANTIDIABETIC AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 2001-01-23 | — | — | US | disclosed |
| US-6048884-A | ANTIDIABETIC AGENTS; HYPOGLYCEMIC AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 2000-04-11 | — | — | US | disclosed |
| EP-0972769-A1 | NOVEL AMIDE DERIVATIVES AND MEDICINAL COMPOSITIONS THEREOF | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 2000-01-19 | — | — | EP | disclosed |