Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 13/20 | 0.52 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | SPR | P35270 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR1D | P28221 | 1/20 | 0.41 |
| ▸ | HTR1B | P28222 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7018337 | 0.86 | MTNR1A (0.71) | MTNR1AMTNR1BALDH1A1KMT2AHTR1A | |
| SCHEMBL6745683 | 0.80 | MTNR1A (0.56) | MTNR1AMTNR1BALDH1A1SPRBCHE | |
| SCHEMBL7026322 | 0.79 | MTNR1A (0.51) | MTNR1AMTNR1B | |
| SCHEMBL5339908 | 0.79 | SPR (0.65) | MTNR1AMTNR1BALDH1A1SPRKMT2A | |
| SCHEMBL5340496 | 0.78 | SPR (0.55) | MTNR1AMTNR1BALDH1A1SPRKMT2A | |
| SCHEMBL5335667 | 0.78 | SPR (0.55) | MTNR1AMTNR1BALDH1A1SPRKMT2A | |
| SCHEMBL5339464 | 0.78 | SPR (0.55) | MTNR1AMTNR1BALDH1A1SPRKMT2A | |
| SCHEMBL5335786 | 0.77 | SPR (0.49) | MTNR1AMTNR1BALDH1A1SPRKMT2A | |
| SCHEMBL6218623 | 0.77 | MTNR1A (0.52) | MTNR1AMTNR1BALDH1A1SPRBCHE | |
| SCHEMBL5341340 | 0.75 | MTNR1A (0.56) | MTNR1AMTNR1BALDH1A1SPRBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1057826-B1 | Substituted dimeric carboxamide derivatives, method for preparing them, and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2003-04-16 | — | — | EP | disclosed |
| US-6310074-B1 | TREATING MELATONINERGIC DISORDERS | ADIR ET COMPAGNIE (FR) | 2001-10-30 | — | — | US | disclosed |
| EP-1057826-A1 | Substituted dimeric carboxamide derivatives, method for preparing them, and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2000-12-06 | — | — | EP | disclosed |