Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 10/20 | 0.51 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.50 |
| ▸ | STS | P08842 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7019542 | 0.86 | MTNR1A (0.69) | MTNR1AMTNR1BTRPV1 | |
| SCHEMBL7018337 | 0.85 | MTNR1A (0.71) | MTNR1AMTNR1B | |
| SCHEMBL7019870 | 0.80 | TRPV1 (0.68) | MTNR1AMTNR1BTRPV1 | |
| SCHEMBL7021034 | 0.79 | MTNR1A (0.52) | MTNR1AMTNR1B | |
| SCHEMBL8137831 | 0.73 | MTNR1A (0.78) | MTNR1AMTNR1B | |
| SCHEMBL14907361 | 0.72 | MTNR1A (0.75) | MTNR1AMTNR1BTRPV1 | |
| SCHEMBL7505689 | 0.71 | MTNR1A (0.92) | MTNR1AMTNR1BTRPV1 | |
| SCHEMBL8571512 | 0.71 | MTNR1A (0.92) | MTNR1AMTNR1BTRPV1 | |
| SCHEMBL1129551 | 0.71 | MTNR1A (0.92) | MTNR1AMTNR1BTRPV1 | |
| SCHEMBL3815984 | 0.70 | MTNR1A (0.75) | MTNR1AMTNR1BTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1057826-B1 | Substituted dimeric carboxamide derivatives, method for preparing them, and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2003-04-16 | — | — | EP | disclosed |
| US-6310074-B1 | TREATING MELATONINERGIC DISORDERS | ADIR ET COMPAGNIE (FR) | 2001-10-30 | — | — | US | disclosed |
| EP-1057826-A1 | Substituted dimeric carboxamide derivatives, method for preparing them, and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2000-12-06 | — | — | EP | disclosed |