Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.31 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.30 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.30 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7937224 | 0.89 | — | — | |
| SCHEMBL7026203 | 0.74 | NLRP3 (0.31) | NLRP3 | |
| SCHEMBL7771790 | 0.70 | — | — | |
| SCHEMBL7023693 | 0.69 | FAAH (0.30) | — | |
| SCHEMBL5708357 | 0.69 | MEN1 (0.32) | NLRP3 | |
| SCHEMBL7771864 | 0.69 | MEN1 (0.30) | — | |
| SCHEMBL1480337 | 0.69 | ALDH1A1 (0.30) | — | |
| SCHEMBL11374140 | 0.69 | FAAH (0.35) | — | |
| SCHEMBL11374136 | 0.69 | FAAH (0.35) | — | |
| SCHEMBL11378352 | 0.69 | FAAH (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1063229-B1 | Alpha, beta-unsaturated ketones | GIVAUDAN SA (CH) | 2003-02-19 | — | — | EP | disclosed |
| EP-1063229-A1 | Alpha, beta-unsaturated ketones | Givaudan SA (CH) | 2000-12-27 | — | — | EP | disclosed |