Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 11/20 | 0.54 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.54 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 13/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 12/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | SLC22A1 | O15245 | 3/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7025936 | 0.87 | SLC6A4 (0.62) | OPRM1OPRD1OPRK1SLC6A4SLC6A2 | |
| SCHEMBL7023195 | 0.85 | OPRM1 (0.45) | OPRM1OPRD1OPRK1SLC6A4SLC6A2 | |
| SCHEMBL7019410 | 0.78 | SLC6A2 (0.62) | OPRM1OPRD1OPRK1SLC6A4SLC6A2 | |
| (R,R)-Tramadol SCHEMBL2678627 | 0.77 | SLC6A2 (0.82) | OPRM1OPRD1OPRK1SLC6A4SLC6A2 | |
| SCHEMBL5509157 | 0.76 | OPRM1 (0.81) | OPRM1OPRD1OPRK1SLC6A4SLC6A2 | |
| Tramadol SCHEMBL4799725 | 0.74 | SLC6A2 (0.76) | OPRM1OPRD1OPRK1SLC6A4SLC6A2 | |
| (R,R)-Tramadol SCHEMBL2678948 | 0.74 | SLC6A2 (0.76) | OPRM1OPRD1OPRK1SLC6A4SLC6A2 | |
| (R,R)-Tramadol SCHEMBL18171987 | 0.73 | SLC6A2 (0.71) | OPRM1OPRD1OPRK1SLC6A4SLC6A2 | |
| SCHEMBL7025932 | 0.73 | SLC6A4 (0.51) | OPRM1OPRD1OPRK1SLC6A4SLC6A2 | |
| (R,R)-Tramadol SCHEMBL2678195 | 0.72 | SLC6A2 (0.89) | OPRM1OPRD1OPRK1SLC6A4SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1127871-B1 | NEW ESTERS DERIVED FROM SUBSTITUTED PHENYL-CYCLOHEXYL COMPOUNDS | VITA LAB (ES) | 2003-09-10 | — | — | EP | claimed |