Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 14/20 | 0.62 |
| ▸ | SLC6A2 | P23975 | 13/20 | 0.62 |
| ▸ | OPRM1 | P35372 | 12/20 | 0.62 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.62 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.56 |
| ▸ | HNF4A | P41235 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7023201 | 0.87 | OPRM1 (0.54) | SLC6A4SLC6A2OPRM1OPRD1OPRK1 | |
| SCHEMBL7025932 | 0.83 | SLC6A4 (0.51) | SLC6A4SLC6A2OPRM1OPRD1OPRK1 | |
| SCHEMBL5509157 | 0.80 | OPRM1 (0.81) | SLC6A4SLC6A2OPRM1OPRD1OPRK1 | |
| (R,R)-Tramadol SCHEMBL2678627 | 0.79 | SLC6A2 (0.82) | SLC6A4SLC6A2OPRM1OPRD1OPRK1 | |
| Tramadol SCHEMBL4799725 | 0.78 | SLC6A2 (0.76) | SLC6A4SLC6A2OPRM1OPRD1OPRK1 | |
| (R,R)-Tramadol SCHEMBL2678948 | 0.78 | SLC6A2 (0.76) | SLC6A4SLC6A2OPRM1OPRD1OPRK1 | |
| Desmetramadol SCHEMBL57246 | 0.77 | OPRM1 (1.00) | SLC6A4SLC6A2OPRM1OPRD1OPRK1 | |
| O-Desmethyl Tramadol SCHEMBL2517055 | 0.77 | OPRM1 (1.00) | SLC6A4SLC6A2OPRM1OPRD1OPRK1 | |
| O-Desmethyl Tramadol SCHEMBL4396389 | 0.77 | OPRM1 (1.00) | SLC6A4SLC6A2OPRM1OPRD1OPRK1 | |
| O-Desmethyl Tramadol SCHEMBL4396391 | 0.77 | OPRM1 (1.00) | SLC6A4SLC6A2OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1127871-B1 | NEW ESTERS DERIVED FROM SUBSTITUTED PHENYL-CYCLOHEXYL COMPOUNDS | VITA LAB (ES) | 2003-09-10 | — | — | EP | claimed |