SCHEMBL7023583

SCHEMBL7023583

COc1cc2cc(CC(C)(C(=O)Nc3ccccc3)C(=O)ONc3ccccc3)sc2cc1OC

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
STING1 Q86WV6 7/20 0.43
MMP8 P22894 1/20 0.39
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
ACHE P22303 5/20 0.37
ALDH1A1 P00352 3/20 0.36
HPGD P15428 3/20 0.36
MAPT P10636 2/20 0.36
KDM4E B2RXH2 2/20 0.36
HSD17B10 Q99714 2/20 0.36
LMNA P02545 2/20 0.36
TP53 P04637 1/20 0.36
ALOX15 P16050 1/20 0.36
TSHR P16473 1/20 0.36
CASP1 P29466 1/20 0.36
CASP7 P55210 1/20 0.36
GAA P10253 1/20 0.36
ALOX12 P18054 1/20 0.36
NPSR1 Q6W5P4 1/20 0.35
RCE1 Q9Y256 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7023581 0.91 MMP8 (0.47) STING1MMP8MEN1KMT2AACHE
SCHEMBL7023586 0.89 STING1 (0.44) STING1MMP8MEN1KMT2AACHE
SCHEMBL7030405 0.89 STING1 (0.40) STING1MEN1KMT2AALDH1A1HPGD
SCHEMBL7023517 0.88 ALDH1A1 (0.39) STING1MEN1KMT2AALDH1A1HPGD
SCHEMBL7025431 0.86 FAAH (0.45) MMP8MAPTLMNATP53
SCHEMBL7035316 0.83 KDM4E (0.42) STING1MEN1KMT2AALDH1A1HPGD
SCHEMBL7023516 0.80 CLK1 (0.41) STING1MMP8MEN1KMT2AALDH1A1
SCHEMBL7023520 0.79 CLK1 (0.39) STING1MEN1KMT2AALDH1A1HPGD
SCHEMBL7030402 0.78 STING1 (0.42) STING1MEN1KMT2AALDH1A1HPGD
SCHEMBL7030408 0.78 STING1 (0.40) STING1MEN1KMT2AALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030109570-A1 Activate a peroxisome proliferator-activated receptor (PPAR) alpha or gamma which is an intranuclear transcription factor. The compound may be used as an active ingredient to give a drug for preventing or treating a variety of diseases MITSUI CHEMICALS, INC. (JP) 2003-06-12 US disclosed
EP-1284265-A1 BENZOTHIOPHENE DERIVATIVES AND MEDICINAL USE THEREOF Mitsui Chemicals, Inc. (JP) 2003-02-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030109570-A1 Activate a peroxisome proliferator-activated receptor (PPAR) alpha or gamma which is an intranuclear transcription factor. The compound may be used as an active ingredient to give a drug for preventing or treating a variety of diseases PPARG, PPARA, PPARD STING1 878/4885MMP8 3646/4885MEN1 4594/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.