Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | CTSS | P25774 | 2/20 | 0.46 |
| ▸ | CTSK | P43235 | 2/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | ANPEP | P15144 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | AKT1 | P31749 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12947605 | 0.88 | PAX8 (0.49) | MAPK1PAX8TDP1ATMMAPT | |
| SCHEMBL23680296 | 0.88 | PAX8 (0.49) | MAPK1PAX8TDP1ATMMAPT | |
| SCHEMBL3387924 | 0.87 | PAX8 (0.53) | MAPK1PAX8TDP1ATMMAPT | |
| SCHEMBL19861958 | 0.86 | PAX8 (0.52) | MAPK1PAX8TDP1MAPTCTSS | |
| SCHEMBL23680153 | 0.86 | REN (0.53) | MAPK1PAX8TDP1MAPTCTSS | |
| SCHEMBL17413437 | 0.86 | REN (0.53) | MAPK1PAX8TDP1MAPTCTSS | |
| SCHEMBL12214996 | 0.85 | PAX8 (0.56) | MAPK1PAX8TDP1ATMMAPT | |
| SCHEMBL17232586 | 0.84 | PAX8 (0.53) | PAX8TDP1MAPTCTSSCTSK | |
| SCHEMBL17254230 | 0.84 | PAX8 (0.53) | PAX8TDP1MAPTCTSSCTSK | |
| SCHEMBL1755615 | 0.84 | TDP1 (0.61) | PAX8TDP1ATMMAPTCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1275657-A1 | PEPTIDE DERIVATIVES AND MEDICINAL COMPOSITIONS | Nippon Shinyaku Co., Ltd. (JP) | 2003-01-15 | — | — | EP | disclosed |