Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | MMP1 | P03956 | 1/20 | 0.52 |
| ▸ | MMP3 | P08254 | 1/20 | 0.52 |
| ▸ | MMP9 | P14780 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 3/20 | 0.52 |
| ▸ | CA2 | P00918 | 3/20 | 0.52 |
| ▸ | FNTA | P49354 | 3/20 | 0.49 |
| ▸ | FNTB | P49356 | 3/20 | 0.49 |
| ▸ | PGGT1B | P53609 | 3/20 | 0.49 |
| ▸ | CTSS | P25774 | 2/20 | 0.49 |
| ▸ | CTSK | P43235 | 2/20 | 0.49 |
| ▸ | GNPAT | O15228 | 1/20 | 0.49 |
| ▸ | CTSL | P07711 | 1/20 | 0.49 |
| ▸ | CTSB | P07858 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17254230 | 1.00 | PAX8 (0.53) | PAX8TDP1MMP1MMP3MMP9 | |
| SCHEMBL21981320 | 0.93 | REN (0.53) | PAX8TDP1MMP1MMP3MMP9 | |
| SCHEMBL21981319 | 0.93 | REN (0.53) | PAX8TDP1MMP1MMP3MMP9 | |
| SCHEMBL17553458 | 0.93 | PAX8 (0.52) | PAX8TDP1MMP1MMP3MMP9 | |
| SCHEMBL1755615 | 0.93 | TDP1 (0.61) | PAX8TDP1MMP1MMP3MMP9 | |
| SCHEMBL29683965 | 0.92 | CCKBR (0.50) | PAX8TDP1MMP1MMP3MMP9 | |
| SCHEMBL13956678 | 0.92 | PAX8 (0.52) | PAX8TDP1MMP1MMP3MMP9 | |
| SCHEMBL17254256 | 0.92 | TDP1 (0.56) | PAX8TDP1MMP1MMP3MMP9 | |
| SCHEMBL23352495 | 0.92 | REN (0.56) | PAX8TDP1GNPAT | |
| SCHEMBL3387924 | 0.92 | PAX8 (0.53) | PAX8TDP1MMP1MMP3MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11993629-B2 | Method for producing peptide compound | NISSAN CHEMICAL CORPORATION (JP) | 2024-05-28 | — | — | US | disclosed |
| WO-2023144379-A1 | HIGH-AFFINITY LIGANDS OF FIBROBLAST ACTIVATION PROTEIN FOR TARGETED DELIVERY APPLICATIONS | PHILOCHEM AG (CH) | 2023-08-03 | — | — | WO | disclosed |
| US-20220106355-A1 | METHOD FOR PRODUCING PEPTIDE COMPOUND | NISSAN CHEMICAL CORPORATION (JP) | 2022-04-07 | — | — | US | disclosed |
| US-20170202975-A1 | DISULFUR BRIDGE LINKERS FOR CONJUGATION OF A CELL-BINDING MOLECULE | SUZHOU M-CONJ BIOTECH CO., LTD. (CN) | 2017-07-20 | — | — | US | disclosed |
| US-20170151346-A1 | DISULFUR BRIDGE LINKERS FOR CONJUGATION OF A CELL-BINDING MOLECULE | SUZHOU M-CONJ BIOTECH CO., LTD. (CN) | 2017-06-01 | — | — | US | disclosed |
| US-20150314017-A1 | DISULFUR BRIDGE LINKERS FOR CONJUGATION OF A CELL-BINDING MOLECULE | SUZHOU M-CONJ BIOTECH CO., LTD (CN) | 2015-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170151346-A1 | DISULFUR BRIDGE LINKERS FOR CONJUGATION OF A CELL-BINDING MOLECULE | CD74, CD2, EPCAM | PAX8 1160/4885TDP1 2250/4885MMP1 3941/4885 |
| US-20170202975-A1 | DISULFUR BRIDGE LINKERS FOR CONJUGATION OF A CELL-BINDING MOLECULE | CD74, CD2, EPCAM | PAX8 1160/4885TDP1 2250/4885MMP1 3941/4885 |
| US-11993629-B2 | Method for producing peptide compound | VIP, NGLY1, IAPP | PAX8 4409/4885TDP1 3840/4885MMP1 3065/4885 |
| US-20150314017-A1 | DISULFUR BRIDGE LINKERS FOR CONJUGATION OF A CELL-BINDING MOLECULE | CD74, CD2, EPCAM | PAX8 1160/4885TDP1 2250/4885MMP1 3941/4885 |
| US-20220106355-A1 | METHOD FOR PRODUCING PEPTIDE COMPOUND | VIP, NGLY1, IAPP | PAX8 4409/4885TDP1 3840/4885MMP1 3065/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.