Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 7/20 | 0.56 |
| ▸ | F2 | P00734 | 4/20 | 0.52 |
| ▸ | PLAU | P00749 | 3/20 | 0.51 |
| ▸ | PLG | P00747 | 2/20 | 0.51 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9710484 | 0.91 | F2 (0.54) | F10F2PLAUPLGST14 | |
| SCHEMBL8770799 | 0.85 | F10 (0.55) | F10F2ST14 | |
| SCHEMBL9710394 | 0.80 | F2 (0.68) | F10F2PLAUPLGST14 | |
| SCHEMBL8654566 | 0.80 | F2 (0.59) | F10F2PLAUPLGST14 | |
| SCHEMBL8654561 | 0.80 | F2 (0.59) | F10F2PLAUPLGST14 | |
| SCHEMBL7983901 | 0.79 | F2 (0.55) | F2 | |
| SCHEMBL8954702 | 0.79 | F10 (0.56) | F10F2PLAUPLG | |
| SCHEMBL7300647 | 0.78 | MMP2 (0.61) | F2 | |
| SCHEMBL9710605 | 0.78 | MMP2 (0.61) | F2 | |
| SCHEMBL7743074 | 0.78 | F10 (0.60) | F10F2PLAUPLGST14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0739886-B1 | Selective thrombin inhibitors | LG CHEMICAL LTD (KR) | 2003-10-01 | — | — | EP | disclosed |
| US-5985899-A | ANTICOAGULANTS | LG CHEMICAL LTD. (KR) | 1999-11-16 | — | — | US | disclosed |
| US-5977114-A | Selective thrombin inhibitors | LG CHEMICAL LTD. (KR) | 1999-11-02 | — | — | US | disclosed |
| EP-0739886-A2 | Selective thrombin inhibitors | LG Chemical Limited (KR) | 1996-10-30 | — | — | EP | disclosed |