Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | MET | P08581 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7023926 | 1.00 | SIGMAR1 (0.56) | SIGMAR1ALDH1A1HPGDSRD5A2RAB9A | |
| SCHEMBL6476191 | 0.91 | SIGMAR1 (0.55) | SIGMAR1ALDH1A1HPGDRAB9ATSHR | |
| SCHEMBL6476194 | 0.91 | SIGMAR1 (0.55) | SIGMAR1ALDH1A1HPGDRAB9ATSHR | |
| SCHEMBL6487606 | 0.89 | SIGMAR1 (0.59) | SIGMAR1ALDH1A1HPGDRAB9ATSHR | |
| SCHEMBL6477711 | 0.87 | SIGMAR1 (0.56) | SIGMAR1ALDH1A1HPGDRAB9ATSHR | |
| SCHEMBL6485663 | 0.86 | RAB9A (0.61) | ALDH1A1HPGDRAB9ATSHRSMN1; SMN2 | |
| SCHEMBL6485660 | 0.86 | RAB9A (0.61) | ALDH1A1HPGDRAB9ATSHRSMN1; SMN2 | |
| SCHEMBL6477456 | 0.84 | SIGMAR1 (0.55) | SIGMAR1ALDH1A1HPGDRAB9ATSHR | |
| SCHEMBL7028555 | 0.82 | SIGMAR1 (0.57) | SIGMAR1ALDH1A1HPGDSRD5A2RAB9A | |
| SCHEMBL6477277 | 0.82 | PPARG (0.58) | SIGMAR1ALDH1A1HPGDRAB9ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1252150-B1 | HETEROCYCLIC DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SERVIER LAB (FR) | 2003-06-04 | — | — | EP | disclosed |