Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | TSHR | P16473 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6485660 | 1.00 | RAB9A (0.61) | RAB9ATSHRSMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL7023926 | 0.86 | SIGMAR1 (0.56) | RAB9ATSHRSMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL7023922 | 0.86 | SIGMAR1 (0.56) | RAB9ATSHRSMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL7019446 | 0.84 | RAB9A (0.61) | RAB9ATSHRSMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL6477010 | 0.83 | TSHR (0.66) | RAB9ATSHRSMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL7017531 | 0.81 | ALDH1A1 (0.59) | RAB9ATSHRSMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL7017529 | 0.81 | ALDH1A1 (0.59) | RAB9ATSHRSMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL6476905 | 0.79 | TSHR (0.62) | RAB9ATSHRSMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL6475863 | 0.78 | L3MBTL1 (0.57) | RAB9ATSHRSMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL6476872 | 0.78 | RAB9A (0.70) | RAB9ATSHRSMN1; SMN2ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6919362-B2 | Heterocyclic derivatives, preparation method and pharmaceutical compositions containing same | LES LABORATOIRES SERVIER (FR) | 2005-07-19 | — | — | US | disclosed |
| US-20030040533-A1 | Novel heterocyclic derivatives, preparation method and pharmaceutical compositions containing same | LES LABORATOIRES SERVIER (FR) | 2003-02-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030040533-A1 | Novel heterocyclic derivatives, preparation method and pharmaceutical compositions containing same | CYP2F1, CYP11B2, CYP4B1 | RAB9A 3361/4885TSHR 844/4885SMN1; SMN2 1823/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.