Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 0.36 |
| ▸ | HSD11B2 | P80365 | 2/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | FAP | Q12884 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.35 |
| ▸ | CCR2 | P41597 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10783825 | 0.87 | TSHR (0.41) | HSD11B1HSD11B2DPP4FAPDPP7 | |
| SCHEMBL10787187 | 0.85 | TSHR (0.47) | HSD11B1HSD11B2TSHRTHRB | |
| SCHEMBL10782756 | 0.82 | HSD11B1 (0.39) | HSD11B1HSD11B2DPP4FAPDPP7 | |
| SCHEMBL10783104 | 0.78 | HSD11B1 (0.37) | HSD11B1HSD11B2DPP4FAPDPP7 | |
| SCHEMBL10534982 | 0.76 | TSHR (0.38) | HSD11B1HSD11B2CCR2TSHRTHRB | |
| SCHEMBL10536845 | 0.76 | TSHR (0.38) | HSD11B1HSD11B2CCR2TSHRTHRB | |
| SCHEMBL10536807 | 0.76 | TSHR (0.38) | HSD11B1HSD11B2CCR2TSHRTHRB | |
| SCHEMBL10536799 | 0.76 | TSHR (0.38) | HSD11B1HSD11B2DPP4FAPDPP7 | |
| SCHEMBL10536837 | 0.76 | TSHR (0.38) | HSD11B1HSD11B2CCR2TSHRTHRB | |
| SCHEMBL10536618 | 0.76 | TSHR (0.38) | HSD11B1HSD11B2CCR2TSHRTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0929509-B1 | LIQUID CRYSTAL ALKENYL BICYCLO 2.2.2]OCTANES AND MIXTURES AND DEVICES CONTAINING SUCH COMPOUNDS | QINETIQ LTD (GB) | 2003-01-15 | — | — | EP | disclosed |
| US-6187393-B1 | FOR LIQUID CRYSTAL DISPLAYS | THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) | 2001-02-13 | — | — | US | disclosed |
| EP-0929509-A1 | LIQUID CRYSTAL ALKENYL BICYCLO 2.2.2]OCTANES AND MIXTURES AND DEVICES CONTAINING SUCH COMPOUNDS | THE SECRETARY OF STATE FOR DEFENCE (GB) | 1999-07-21 | — | — | EP | disclosed |
| WO-1998013326-A1 | LIQUID CRYSTAL ALKENYL BICYCLO[2.2.2]OCTANES AND MIXTURES AND DEVICES CONTAINING SUCH COMPOUNDS | THE SECRETARY OF STATE FOR DEFENCE (GB) | 1998-04-02 | — | — | WO | disclosed |
| US-4694098-A | WIDE MESOMORPHIC RANGE | HITACHI, LTD. (JP) | 1987-09-15 | — | — | US | disclosed |
| EP-0120560-B1 | LIQUID CRYSTAL MATERIALS AND ADDITIVE COMPOUNDS CONTAINING A BICYCLO(2,2,2,)OCTANE STRUCTURE SUITABLE FOR USE IN THEM | The Secretary of State for Defence in Her Britannic Majesty's Government of the United Kingdom of Great Britain and (GB) | 1987-08-19 | — | — | EP | disclosed |
| EP-0058981-B1 | COLORLESS LIQUID CRYSTALLINE COMPOUNDS | Hitachi, Ltd. (JP) | 1986-01-22 | — | — | EP | disclosed |
| US-4564694-A | CYCLOHEXYL AND PHENYL RING-CONTAINING ALIPHATIC ETHERS | HITACHI, LTD. (JP) | 1986-01-14 | — | — | US | disclosed |
| US-4544497-A | DISPLAY DEVICES | THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) | 1985-10-01 | — | — | US | disclosed |
| EP-0120560-A2 | Liquid crystal materials and additive compounds containing a bicyclo(2,2,2,)octane structure suitable for use in them | The Secretary of State for Defence in Her Britannic Majesty's Government of the United Kingdom of Great Britain and (GB) | 1984-10-03 | — | — | EP | disclosed |
| EP-0058981-A2 | Colorless liquid crystalline compounds | Hitachi, Ltd. (JP) | 1982-09-01 | — | — | EP | disclosed |