Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.69 |
| ▸ | GLA | P06280 | 3/20 | 0.69 |
| ▸ | GAA | P10253 | 3/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.69 |
| ▸ | HPGD | P15428 | 3/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.69 |
| ▸ | CASP1 | P29466 | 2/20 | 0.69 |
| ▸ | CASP7 | P55210 | 2/20 | 0.69 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.64 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.64 |
| ▸ | HSD17B3 | P37058 | 4/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 3/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL593432 | 0.90 | KDM4E (0.57) | KDM4EGLAGAAALDH1A1HPGD | |
| SCHEMBL29385493 | 0.90 | KDM4E (0.57) | KDM4EGLAGAAALDH1A1HPGD | |
| SCHEMBL8054975 | 0.88 | PSMB8 (0.62) | KDM4EGLAGAAALDH1A1HPGD | |
| SCHEMBL30406107 | 0.82 | KDM4E (1.00) | KDM4EGLAGAAALDH1A1HPGD | |
| SCHEMBL2554744 | 0.82 | KDM4E (1.00) | KDM4EGLAGAAALDH1A1HPGD | |
| SCHEMBL7023152 | 0.79 | KDM4E (1.00) | KDM4EGLAGAAALDH1A1HPGD | |
| SCHEMBL8352874 | 0.79 | PSMB8 (0.59) | KDM4EGLAGAAALDH1A1HPGD | |
| SCHEMBL2528490 | 0.78 | SRC (0.53) | KDM4EGLAGAAALDH1A1HPGD | |
| SCHEMBL29577443 | 0.78 | SRC (0.53) | KDM4EGLAGAAALDH1A1HPGD | |
| SCHEMBL18099118 | 0.78 | PSMB8 (1.00) | KDM4EHSD17B10PSMB8PSMB5MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0538053-B1 | Separation and analysis | MARCONI OPTICAL COMPONENTS LTD (GB) | 2003-01-22 | — | — | EP | disclosed |
| US-6225043-B1 | IMMUNOASSAY IN WHICH ONE OF THE SPECIES IS MASKED AND NOT CAPABLE OF UNDERGOING SPECIFIC BINDING UNLESS REACTED WITH ENZYME WHICH EXPOSES ANTIGENIC LIGAND | GEC-MARCONI LIMITED (GB) | 2001-05-01 | — | — | US | disclosed |
| EP-0538053-A1 | Separation and analysis | GEC-MARCONI LIMITED (GB) | 1993-04-21 | — | — | EP | disclosed |