Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 11/20 | 0.45 |
| ▸ | F2 | P00734 | 5/20 | 0.42 |
| ▸ | F7 | P08709 | 4/20 | 0.42 |
| ▸ | F3 | P13726 | 4/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.37 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7027708 | 0.85 | TPSAB1 (0.43) | TPSAB1F2F7F3PRSS1 | |
| SCHEMBL7020326 | 0.85 | TPSAB1 (0.43) | TPSAB1F2F7F3PRSS1 | |
| SCHEMBL3247707 | 0.80 | F2 (0.60) | TPSAB1F2F7F3PRSS1 | |
| SCHEMBL7449497 | 0.79 | TPSAB1 (0.57) | TPSAB1F2F7F3PRSS1 | |
| SCHEMBL7020450 | 0.78 | TPSAB1 (0.54) | TPSAB1F2F7F3PRSS1 | |
| SCHEMBL7024770 | 0.78 | TPSAB1 (0.50) | TPSAB1F2F7F3PRSS1 | |
| SCHEMBL7021593 | 0.78 | TPSAB1 (0.53) | TPSAB1F2F7F3PRSS1 | |
| SCHEMBL5885589 | 0.77 | F2 (0.59) | TPSAB1F2F7F3PRSS1 | |
| SCHEMBL7403728 | 0.77 | TPSAB1 (0.49) | TPSAB1F2F7F3PRSS1 | |
| SCHEMBL7021064 | 0.76 | PRMT5 (0.46) | TPSAB1F2F7F3PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6417203-B1 | HETEROCYCLIC AMIDES | PFIZER INC. | 2002-07-09 | — | — | US | disclosed |
| US-6180627-B1 | INDOLE, INDAZOLE, BENZOTRIAZOLE AND BENZIMIDAZOLE DERIVATIVES | PFIZER INC. | 2001-01-30 | — | — | US | disclosed |
| EP-0997474-A1 | Antithrombotic agents | PFIZER INC. (US) | 2000-05-03 | — | — | EP | disclosed |