Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | MMP1 | P03956 | 3/20 | 0.48 |
| ▸ | MMP2 | P08253 | 3/20 | 0.48 |
| ▸ | MMP9 | P14780 | 2/20 | 0.48 |
| ▸ | MMP12 | P39900 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6236586 | 0.78 | TDP1 (0.54) | KMT2ATDP1ALDH1A1L3MBTL1P2RX7 | |
| SCHEMBL31722590 | 0.77 | P2RX7 (0.51) | GAAKMT2AMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL7023431 | 0.74 | P2RX7 (0.43) | GAAKMT2ATDP1ALDH1A1L3MBTL1 | |
| SCHEMBL27846622 | 0.73 | P2RX7 (0.51) | GAAKMT2AMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL29508230 | 0.73 | CYP1A2 (0.53) | KMT2AMEN1ALDH1A1P2RX7HSD17B10 | |
| SCHEMBL917137 | 0.73 | CYP1A2 (0.53) | KMT2AMEN1ALDH1A1P2RX7HSD17B10 | |
| SCHEMBL27798556 | 0.73 | P2RX7 (0.56) | ALDH1A1L3MBTL1P2RX7NPSR1 | |
| SCHEMBL15544859 | 0.72 | ALDH1A1 (0.70) | GAAKMT2AMEN1TDP1MMP1 | |
| Hydrochloric Acid SCHEMBL27922723 | 0.72 | CYP1A2 (0.51) | KMT2AMEN1ALDH1A1P2RX7HSD17B10 | |
| SCHEMBL7103527 | 0.71 | P2RX7 (0.43) | GAAALDH1A1P2RX7NPSR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1370562-A1 | THIENO[2,3-D]PYRIMIDINDIONE DERIVATIVES AS MATRIX METALLOPROTEINASE INHIBITORS | Warner-Lambert Company LLC (US) | 2003-12-17 | — | — | EP | claimed |
| WO-2002064598-A1 | THIENO'2,3-D PYRIMIDINDIONE DERIVATIVES AS MATRIX METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2002-08-22 | — | — | WO | claimed |