Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.35 |
| ▸ | WNT3A | P56704 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.34 |
| ▸ | FDPS | P14324 | 1/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | FPR2 | P25090 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6236586 | 0.75 | TDP1 (0.54) | P2RX7CYP3A4NPSR1PKMALDH1A1 | |
| SCHEMBL29508230 | 0.73 | CYP1A2 (0.53) | P2RX7KDM4ECTNNB1WNT3AALDH1A1 | |
| SCHEMBL27846622 | 0.73 | P2RX7 (0.51) | P2RX7KDM4EGAACTNNB1WNT3A | |
| SCHEMBL917137 | 0.73 | CYP1A2 (0.53) | P2RX7KDM4ECTNNB1WNT3AALDH1A1 | |
| SCHEMBL27798556 | 0.73 | P2RX7 (0.56) | P2RX7CTNNB1WNT3AGRM4NPSR1 | |
| SCHEMBL31722590 | 0.73 | P2RX7 (0.51) | P2RX7KDM4EGAACTNNB1WNT3A | |
| SCHEMBL6474567 | 0.72 | P2RX7 (0.41) | P2RX7GAACTNNB1WNT3AGRM4 | |
| Hydrochloric Acid SCHEMBL27922723 | 0.72 | CYP1A2 (0.51) | P2RX7KDM4ECTNNB1WNT3AALDH1A1 | |
| SCHEMBL21624605 | 0.72 | TBXAS1 (0.44) | TBXAS1GAACYP3A4TAAR1FDPS | |
| SCHEMBL6432861 | 0.72 | FDPS (0.45) | TBXAS1KDM4EGAAHTTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1370562-A1 | THIENO[2,3-D]PYRIMIDINDIONE DERIVATIVES AS MATRIX METALLOPROTEINASE INHIBITORS | Warner-Lambert Company LLC (US) | 2003-12-17 | — | — | EP | claimed |
| WO-2002064598-A1 | THIENO'2,3-D PYRIMIDINDIONE DERIVATIVES AS MATRIX METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2002-08-22 | — | — | WO | claimed |