Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 10/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KDM5A | P29375 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | AGXT | P21549 | 1/20 | 0.32 |
| ▸ | GBA1 | P04062 | 1/20 | 0.32 |
| ▸ | LCT | P09848 | 1/20 | 0.32 |
| ▸ | UGCG | Q16739 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7031162 | 0.90 | CYP2C9 (0.43) | NAAAFAAHESR2ESR1CYP3A4 | |
| SCHEMBL7028248 | 0.89 | NAAA (0.36) | NAAAFAAHESR2ESR1CYP3A4 | |
| SCHEMBL7026572 | 0.87 | CYP2C9 (0.36) | NAAAFAAHESR2CYP2C9ALDH1A1 | |
| SCHEMBL8390750 | 0.86 | KDM5A (0.39) | ESR2ESR1CYP3A4CYP2C9KDM5A | |
| SCHEMBL7032806 | 0.86 | KDM5A (0.39) | ESR2CYP2C9ALDH1A1KDM5AKDM4C | |
| SCHEMBL7031706 | 0.86 | KDM5A (0.39) | ESR2ESR1CYP3A4CYP2C9KDM5A | |
| SCHEMBL7025910 | 0.86 | ESR2 (0.35) | ESR2ESR1CYP3A4CYP2C9ALDH1A1 | |
| SCHEMBL7029788 | 0.85 | KDM5A (0.36) | NAAAFAAHCYP3A4ALDH1A1KDM5A | |
| SCHEMBL7026291 | 0.85 | KDM1A (0.41) | KDM5AKDM4CKDM5BGRIN1GRIN2B | |
| SCHEMBL7026091 | 0.83 | ESR2 (0.34) | NAAAFAAHESR2ESR1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0754668-B1 | Fluorobenzylether derivatives | ROLIC AG (CH) | 2003-02-05 | — | — | EP | disclosed |
| EP-0754668-A2 | Fluorobenzylether derivatives | Rolic AG (CH) | 1997-01-22 | — | — | EP | disclosed |