Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 10/20 | 0.36 |
| ▸ | GBA1 | P04062 | 2/20 | 0.35 |
| ▸ | LCT | P09848 | 2/20 | 0.35 |
| ▸ | UGCG | Q16739 | 2/20 | 0.35 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.33 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | AGXT | P21549 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7027474 | 0.90 | CYP2C9 (0.42) | NAAAGBA1LCTUGCGGBA2 | |
| SCHEMBL7024982 | 0.89 | NAAA (0.36) | NAAAGBA1LCTUGCGGBA2 | |
| SCHEMBL7029011 | 0.87 | CYP2C9 (0.35) | NAAAGBA1LCTUGCGGBA2 | |
| SCHEMBL8390749 | 0.86 | KDM5A (0.38) | ESR2KDM5AKDM4CKDM5BESR1 | |
| SCHEMBL7033088 | 0.86 | FFAR4 (0.35) | FFAR4ESR2ESR1CYP3A4CYP2C9 | |
| SCHEMBL7028213 | 0.86 | KDM5A (0.38) | ESR2KDM5AKDM4CKDM5BESR1 | |
| SCHEMBL7027057 | 0.85 | FFAR4 (0.33) | NAAAGBA1LCTUGCGGBA2 | |
| SCHEMBL7028333 | 0.84 | NAAA (0.34) | NAAAGBA1LCTUGCGGBA2 | |
| SCHEMBL8385977 | 0.82 | ALOX5AP (0.38) | NAAAGBA1LCTUGCGGBA2 | |
| SCHEMBL7512108 | 0.81 | ALDH1A1 (0.39) | ESR2ESR1CYP3A4CYP2C9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0754668-B1 | Fluorobenzylether derivatives | ROLIC AG (CH) | 2003-02-05 | — | — | EP | disclosed |
| EP-0754668-A2 | Fluorobenzylether derivatives | Rolic AG (CH) | 1997-01-22 | — | — | EP | disclosed |