Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | CLK1 | P49759 | 1/20 | 0.54 |
| ▸ | GSK3B | P49841 | 1/20 | 0.54 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.54 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.54 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.54 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | THRB | P10828 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.51 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26259398 | 0.81 | MEN1 (0.33) | MEN1KMT2AHTTCLK1GSK3B | |
| SCHEMBL20017671 | 0.79 | CLK1 (0.58) | MEN1KMT2AHTTCLK1GSK3B | |
| SCHEMBL26259557 | 0.77 | IKBKE (0.32) | MEN1KMT2AHTTGSK3BCDK5 | |
| SCHEMBL31127913 | 0.76 | CLK1 (0.59) | MEN1KMT2AHTTCLK1GSK3B | |
| SCHEMBL11258541 | 0.76 | CLK1 (0.59) | MEN1KMT2AHTTCLK1GSK3B | |
| SCHEMBL12676548 | 0.76 | CDK9 (0.57) | GSK3BCDK5DYRK1ACDK5R1PRKD3 | |
| SCHEMBL1202543 | 0.76 | IMPDH2 (0.63) | MEN1KMT2AHTTMAPTSMN1; SMN2 | |
| SCHEMBL25034150 | 0.76 | TUBB4A (0.68) | MEN1KMT2AHTTCLK1GSK3B | |
| SCHEMBL2870082 | 0.74 | DYRK1A (0.57) | MEN1KMT2AHTTCLK1GSK3B | |
| SCHEMBL26259238 | 0.73 | NISCH (0.41) | MEN1KMT2AGSK3BCDK5CDK5R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-11228572-A | — | — | None | — | — | JP | disclosed |
| EP-1026170-B1 | Erythromycin derivatives, their preparation and use as medicaments | AVENTIS PHARMA SA (FR) | 2003-01-15 | — | — | EP | disclosed |
| JP-2002114780-A | 4-(3-INDOLYL)IMIDAZOLE DERIVATIVE | TAISHO PHARMACEUT CO LTD | 2002-04-16 | — | — | JP | disclosed |
| JP-2002114780-A | 4-(3-INDOLYL)IMIDAZOLE DERIVATIVE | TAISHO PHARMACEUT CO LTD | 2002-04-16 | — | — | JP | disclosed |
| US-6313101-B1 | ANTIBIOTICS | AVENTIS PHARMA S.A. (FR) | 2001-11-06 | — | — | US | disclosed |
| EP-1026170-A1 | Erythromycin derivatives, their preparation and use as medicaments | HOECHST MARION ROUSSEL (FR) | 2000-08-09 | — | — | EP | disclosed |
| JP-H11228572-A | 4-(3-INDOLYL)IMIDAZOLE DERIVATIVE | TAISHO PHARMACEUT CO LTD | 1999-08-24 | — | — | JP | disclosed |
| WO-1999035142-A1 | 4-(3-INDOLYL)IMIDAZOLE DERIVATIVES | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1999-07-15 | — | — | WO | disclosed |
| WO-1999035142-A1 | 4-(3-INDOLYL)IMIDAZOLE DERIVATIVES | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1999-07-15 | — | — | WO | disclosed |