SCHEMBL7025308

SCHEMBL7025308

C=C(C(=C)C(=O)OC)C(=O)NC(C(C)C)S(=O)(=O)O.C=C(C)C(=O)OCCOC(=O)CC(C)=O

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.33
TSHR P16473 3/20 0.32
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9119105 0.90 THRB (0.35) THRBTSHRALDH1A1
SCHEMBL7535348 0.89 TSHR (0.40) THRBTSHR
SCHEMBL8761553 0.80 ALDH1A1 (0.38) THRBTSHRALDH1A1
SCHEMBL14800423 0.77
SCHEMBL8356573 0.76 TSHR (0.35) THRBTSHR
SCHEMBL29497665 0.75 ALDH1A1 (0.56) THRBTSHRALDH1A1
SCHEMBL15263096 0.73 THRB (0.57) THRBTSHRALDH1A1
SCHEMBL62134 0.73 THRB (0.57) THRBTSHRALDH1A1
SCHEMBL7990545 0.72 THRB (0.36) THRBTSHRALDH1A1
SCHEMBL5969505 0.72 THRB (0.55) THRBTSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0745894-B1 Black and white photographic elements containing release compounds and method of preparing photographic emulsion EASTMAN KODAK CO (US) 2003-01-22 EP disclosed
EP-0566077-B1 Photographic silver halide material comprising tabular silver halide grains plus distributed absorber dyes EASTMAN KODAK CO (US) 1999-06-23 EP disclosed
EP-0566082-B1 Photographic silver halide material comprising tabular grains and positioned absorber dyes EASTMAN KODAK CO (US) 1998-12-23 EP disclosed
EP-0566081-B1 Photographic silver halide material comprising tabular grains of specified dimensions EASTMAN KODAK CO (US) 1998-12-23 EP disclosed
EP-0566078-B1 Photographic silver halide material comprising tabular grains of specified dimensions in several colour records EASTMAN KODAK CO (US) 1998-08-26 EP disclosed
EP-0745894-A1 Black and white photographic elements containing release compounds and method of preparing photographic emulsion EASTMAN KODAK COMPANY (US) 1996-12-04 EP disclosed
US-5500338-A Black and white photographic elements containing release compounds and method of preparing photographic emulsion EASTMAN KODAK COMPANY (US) 1996-03-19 US disclosed
US-5395744-A In a specified spatial arrangement to improve sharpness; layers comprise sensitized high aspect ratio emulsions EASTMAN KODAK COMPANY (US) 1995-03-07 US disclosed
US-5308747-A Color negatives, improved sharpness EASTMAN KODAK COMPANY (US) 1994-05-03 US disclosed
US-5302499-A Improved speed and sharpness EASTMAN KODAK COMPANY (US) 1994-04-12 US disclosed
US-5275929-A High aspect ratio for improved sharpness EASTMAN KODAK COMPANY (US) 1994-01-04 US disclosed
EP-0566082-A1 Photographic silver halide material comprising tabular grains and positioned absorber dyes EASTMAN KODAK COMPANY (US) 1993-10-20 EP disclosed
EP-0566078-A2 Photographic silver halide material comprising tabular grains of specified dimensions in several colour records EASTMAN KODAK COMPANY (US) 1993-10-20 EP disclosed
EP-0566077-A2 Photographic silver halide material comprising tabular silver halide grains plus distributed absorber dyes EASTMAN KODAK COMPANY (US) 1993-10-20 EP disclosed
EP-0566081-A2 Photographic silver halide material comprising tabular grains of specified dimensions EASTMAN KODAK COMPANY (US) 1993-10-20 EP disclosed