SCHEMBL7535348

SCHEMBL7535348

C=C(C(=C)C(=O)OCCCC)C(=O)NC(C(C)C)S(=O)(=O)O.C=C(C)C(=O)OCCOC(=O)CC(C)=O

nearest known ligand 0.40

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.40
THRB P10828 1/20 0.33
POLB P06746 1/20 0.32
APEX1 P27695 1/20 0.32
HTT P42858 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7025308 0.89 THRB (0.33) TSHRTHRB
SCHEMBL8356573 0.82 TSHR (0.35) TSHRTHRB
SCHEMBL9119105 0.79 THRB (0.35) TSHRTHRB
SCHEMBL8761553 0.77 ALDH1A1 (0.38) TSHRTHRB
SCHEMBL14800423 0.76
SCHEMBL3148152 0.72 RECQL (0.42) TSHRTDP1
SCHEMBL4638027 0.71 TSHR (0.45) TSHRTHRBPOLBAPEX1HTT
SCHEMBL8999846 0.70 TSHR (0.59) TSHRTHRBPOLBAPEX1HTT
SCHEMBL272304 0.70 TSHR (0.61) TSHRTHRBPOLBAPEX1HTT
SCHEMBL273176 0.70 TSHR (0.56) TSHRTHRBPOLBAPEX1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6395459-B1 CURING; WATERPROOF PROTECTIVE COATING EASTMAN KODAK COMPANY 2002-05-28 US disclosed
EP-1193551-A2 A method of forming a protective overcoat for imaged elements and related articles EASTMAN KODAK COMPANY (US) 2002-04-03 EP disclosed
EP-0566077-B1 Photographic silver halide material comprising tabular silver halide grains plus distributed absorber dyes EASTMAN KODAK CO (US) 1999-06-23 EP disclosed
EP-0566082-B1 Photographic silver halide material comprising tabular grains and positioned absorber dyes EASTMAN KODAK CO (US) 1998-12-23 EP disclosed
EP-0566081-B1 Photographic silver halide material comprising tabular grains of specified dimensions EASTMAN KODAK CO (US) 1998-12-23 EP disclosed
EP-0566078-B1 Photographic silver halide material comprising tabular grains of specified dimensions in several colour records EASTMAN KODAK CO (US) 1998-08-26 EP disclosed
US-5395744-A In a specified spatial arrangement to improve sharpness; layers comprise sensitized high aspect ratio emulsions EASTMAN KODAK COMPANY (US) 1995-03-07 US disclosed
US-5308747-A Color negatives, improved sharpness EASTMAN KODAK COMPANY (US) 1994-05-03 US disclosed
US-5302499-A Improved speed and sharpness EASTMAN KODAK COMPANY (US) 1994-04-12 US disclosed
US-5275929-A High aspect ratio for improved sharpness EASTMAN KODAK COMPANY (US) 1994-01-04 US disclosed
EP-0566082-A1 Photographic silver halide material comprising tabular grains and positioned absorber dyes EASTMAN KODAK COMPANY (US) 1993-10-20 EP disclosed
EP-0566078-A2 Photographic silver halide material comprising tabular grains of specified dimensions in several colour records EASTMAN KODAK COMPANY (US) 1993-10-20 EP disclosed
EP-0566077-A2 Photographic silver halide material comprising tabular silver halide grains plus distributed absorber dyes EASTMAN KODAK COMPANY (US) 1993-10-20 EP disclosed
EP-0566081-A2 Photographic silver halide material comprising tabular grains of specified dimensions EASTMAN KODAK COMPANY (US) 1993-10-20 EP disclosed