Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3525420 | 0.98 | EPHX2 (0.39) | EPHX2GAAEPHX1PDE2APDE3B | |
| SCHEMBL1369330 | 0.94 | REN (0.35) | EPHX2GAAEPHX1 | |
| SCHEMBL6360022 | 0.87 | REN (0.32) | — | |
| SCHEMBL8484522 | 0.87 | SLC6A4 (0.36) | — | |
| Hydrochloric Acid SCHEMBL8484517 | 0.85 | SLC6A4 (0.36) | — | |
| SCHEMBL14095485 | 0.85 | ALDH1A1 (0.41) | PDE2APDE3BPDE3AP2RY12ALDH1A1 | |
| SCHEMBL992260 | 0.84 | — | — | |
| SCHEMBL27510109 | 0.83 | EPHX1 (0.39) | GAAEPHX1 | |
| SCHEMBL15370101 | 0.83 | NFKB1 (0.40) | GAAPDE2APDE3BPDE3AP2RY12 | |
| SCHEMBL15369794 | 0.83 | CETP (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0739886-B1 | Selective thrombin inhibitors | LG CHEMICAL LTD (KR) | 2003-10-01 | — | — | EP | disclosed |
| US-5985899-A | ANTICOAGULANTS | LG CHEMICAL LTD. (KR) | 1999-11-16 | — | — | US | disclosed |
| US-5977114-A | Selective thrombin inhibitors | LG CHEMICAL LTD. (KR) | 1999-11-02 | — | — | US | disclosed |
| US-5747535-A | AMIDINOPHENYL COMPOUNDS | LG CHEMICAL LTD. (KR) | 1998-05-05 | — | — | US | disclosed |
| WO-1997049673-A1 | SELECTIVE THROMBIN INHIBITORS | LG CHEMICAL LTD. (KR) | 1997-12-31 | — | — | WO | disclosed |
| EP-0739886-A2 | Selective thrombin inhibitors | LG Chemical Limited (KR) | 1996-10-30 | — | — | EP | disclosed |