SCHEMBL702567

SCHEMBL702567

NCc1ccc(C(=O)O)c(O)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.57
KDM4E B2RXH2 3/20 0.57
MAPT P10636 2/20 0.57
CYP3A4 P08684 1/20 0.57
GAA P10253 1/20 0.57
ESR2 Q92731 1/20 0.57
PTPN1 P18031 1/20 0.57
PPARA Q07869 1/20 0.56
CA12 O43570 1/20 0.55
CA1 P00915 1/20 0.55
CA2 P00918 1/20 0.55
TSHR P16473 1/20 0.55
CA7 P43166 1/20 0.55
CA9 Q16790 1/20 0.55
CA14 Q9ULX7 1/20 0.55
KLKB1 P03952 3/20 0.50
LCK P06239 1/20 0.50
CTSB P07858 1/20 0.50
MMP9 P14780 1/20 0.50
DNMT1 P26358 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6289406 0.98 ALDH1A1 (0.55) ALDH1A1KDM4EMAPTCYP3A4GAA
SCHEMBL8759348 0.85 PPARA (0.61) ALDH1A1KDM4EMAPTCYP3A4GAA
SCHEMBL3846227 0.84 KLKB1 (0.71) ALDH1A1KDM4ECYP3A4PTPN1CA12
SCHEMBL8815944 0.84 KLKB1 (0.71) ALDH1A1KDM4ECYP3A4PTPN1CA12
SCHEMBL6451619 0.83 ALDH1A1 (0.52) ALDH1A1KDM4EMAPTCYP3A4GAA
SCHEMBL8759962 0.82 PPARA (0.67) ALDH1A1KDM4EMAPTCYP3A4GAA
SCHEMBL17422566 0.82 KLKB1 (0.43) ALDH1A1KDM4EMAPTCYP3A4GAA
SCHEMBL1401513 0.82 ALDH1A1 (0.57) ALDH1A1KDM4EMAPTCYP3A4GAA
SCHEMBL2837159 0.82 ALDH1A1 (0.57) ALDH1A1KDM4EMAPTCYP3A4GAA
SCHEMBL13209792 0.81 ALDH1A1 (0.53) ALDH1A1KDM4EMAPTCYP3A4GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7572459-B2 Prevention infections in humans, animals STARPHARMA PTY LTD. (AU) 2009-08-11 US claimed
EP-1113806-B1 ANIONIC OR CATIONIC DENDRIMER ANTIMICROBIAL OR ANTIPARASITIC COMPOSITIONS STARPHARMA PTY LTD (AU) 2007-09-05 EP claimed
EP-0765357-B9 ANTIVIRAL DENDRIMERS STARPHARMA PTY LTD (AU) 2006-08-16 EP claimed
EP-0927217-B1 ANGIOGENIC INHIBITORY COMPOUNDS STARPHARMA PTY LTD (AU) 2006-05-03 EP claimed
EP-0765357-B8 ANTIVIRAL DENDRIMERS STARPHARMA PTY LTD (AU) 2006-03-08 EP claimed
EP-0765357-B1 ANTIVIRAL DENDRIMERS BIOMOLECULAR RES INST LTD (AU) 2005-12-14 EP claimed
CN-1161128-C Angiogenic inhibitory compounds О 2004-08-11 CN claimed
EP-1113805-A4 INHIBITION OF TOXIC MATERIALS OR SUBSTANCES USING DENDRIMERS STARPHARMA LTD (AU) 2004-05-19 EP claimed
CN-1134486-C Antiviral dendrimers BIOMOLECULAR RES INST LTD (AU) 2004-01-14 CN claimed
US-20030129158-A1 Anionic or cationic dendrimer antimicrobial or antiparasitic compositions STARPHARMA LIMITED 2003-07-10 US claimed
US-6190650-B1 FOR PROPHYLAXIS AND THERAPY OF VIRAL DISEASES IN HUMANS AND ANIMALS BIOMOLECULAR RESEARCH INSTITUTE LTD. (AU) 2001-02-20 US claimed
WO-2000015240-A1 ANIONIC OR CATIONIC DENDRIMER ANTIMICROBIAL OR ANTIPARASITIC COMPOSITIONS STARPHARMA LIMITED (AU) 2000-03-23 WO claimed
WO-2000015239-A1 INHIBITION OF TOXIC MATERIALS OR SUBSTANCES USING DENDRIMERS STARPHARMA LIMITED (AU) 2000-03-23 WO claimed
CN-1225654-A Angiogenic inhibitory compounds BIOMOLECULAR RES INST LTD (AU) 1999-08-11 CN claimed
EP-0927217-A1 ANGIOGENIC INHIBITORY COMPOUNDS BIOMOLECULAR RESEARCH INSTITUTE LTD. (AU) 1999-07-07 EP claimed
WO-1998003573-A1 ANGIOGENIC INHIBITORY COMPOUNDS BIOMOLECULAR RESEARCH INSTITUTE LTD. (AU) 1998-01-29 WO claimed
EP-0765357-A4 ANTIVIRAL DENDRIMERS BIOMOLECULAR RES INST LTD (AU) 1997-07-30 EP claimed
CN-1154123-A Antiviral dendrimers BIOMOLECULAR RES INST LTD (AU) 1997-07-09 CN claimed
EP-0765357-A1 ANTIVIRAL DENDRIMERS BIOMOLECULAR RESEARCH INSTITUTE LTD. (AU) 1997-04-02 EP claimed
WO-1995034595-A1 ANTIVIRAL DENDRIMERS BIOMOLECULAR RESEARCH INSTITUTE LTD. (AU) 1995-12-21 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030129158-A1 Anionic or cationic dendrimer antimicrobial or antiparasitic compositions FUT6, B3GNT2, SIGLEC7 ALDH1A1 2800/4885KDM4E 4773/4885MAPT 3726/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.