Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | EDNRA | P25101 | 3/20 | 0.31 |
| ▸ | EDNRB | P24530 | 2/20 | 0.31 |
| ▸ | CCR2 | P41597 | 1/20 | 0.30 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16021145 | 0.83 | L3MBTL1 (0.31) | CCR2 | |
| SCHEMBL30758079 | 0.83 | — | — | |
| SCHEMBL701268 | 0.83 | EDNRB (0.30) | EDNRAEDNRB | |
| SCHEMBL29171450 | 0.83 | — | — | |
| SCHEMBL31590221 | 0.83 | — | — | |
| SCHEMBL16019322 | 0.82 | — | — | |
| Bromide SCHEMBL28689439 | 0.82 | — | — | |
| SCHEMBL6662019 | 0.82 | KMT2A (0.31) | — | |
| SCHEMBL30608210 | 0.82 | — | — | |
| SCHEMBL4703228 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117551090-A | Method for synthesizing topramezone by photocatalysis | 江苏农牧科技职业学院 | 2024-02-13 | — | — | CN | claimed |
| EP-1131307-B1 | METHOD OF PRODUCING 2-ALKYL-3-(4,5-DIHYDROISOXAZOLE-3-YL)-HALOBENZENES | BASF AG (DE) | 2004-08-25 | — | — | EP | claimed |
| US-20030229232-A1 | Herbicides | RACK MICHAEL (DE) | 2003-12-11 | — | — | US | claimed |
| US-6548677-B1 | Halogenating o-xylene; reacting with hydrogen peroxide and halogenating agent to form a benzyl halide; oxidation to aldehyde; oximination, cyclization, and sulfiding | BASF AKTIENGESELLSCHAFT (DE) | 2003-04-15 | — | — | US | claimed |
| US-20020156290-A1 | Herbicides | RACK MICHAEL (DE) | 2002-10-24 | — | — | US | claimed |
| CN-117551090-A | Method for synthesizing topramezone by photocatalysis | 江苏农牧科技职业学院 | 2024-02-13 | — | — | CN | disclosed |
| CN-114057715-A | Preparation method of topramezone | 安徽宁亿泰科技有限公司 | 2022-02-18 | — | — | CN | disclosed |
| CN-110922367-A | Intermediate of topramezone and preparation method of topramezone | 江苏中旗科技股份有限公司 | 2020-03-27 | — | — | CN | disclosed |
| EP-2325176-B1 | Process for the preparation of Isoxazolin-3-yl-Acylbenzenes | BASF SE (DE) | 2015-02-25 | — | — | EP | disclosed |
| US-8124810-B2 | Preparation of isoxazolin-3-ylacylbenzenes | BASF SE (DE) | 2012-02-28 | — | — | US | disclosed |
| US-8049017-B2 | Preparation of isoxazolin-3-ylacylbenzenes | BASF SE (DE) | 2011-11-01 | — | — | US | disclosed |
| US-20110152535-A1 | PREPARATION OF ISOXAZOLIN-3-YLACYLBENZENES | RHEINHEIMER JOACHIM | 2011-06-23 | — | — | US | disclosed |
| US-20030028033-A1 | Process and novel intermediates for preparing isoxazolin-3-ylacyl benzenes | DEYN WOLFGANG VON (DE) | 2003-02-06 | — | — | US | disclosed |
| US-20030018200-A1 | Preparation of isoxazolin-3-ylacylbenzenes | BASF SE (DE) | 2003-01-23 | — | — | US | disclosed |
| US-20020156290-A1 | Herbicides | RACK MICHAEL (DE) | 2002-10-24 | — | — | US | disclosed |
| US-6469176-B1 | CROP PROTECTION COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2002-10-22 | — | — | US | disclosed |
| EP-1129082-A1 | METHOD AND NOVEL INTERMEDIATE PRODUCTS FOR PRODUCING ISOXAZOLIN-3-YL-ACYLBENZENES | BASF AKTIENGESELLSCHAFT (DE) | 2001-09-05 | — | — | EP | disclosed |
| EP-1077955-A1 | METHOD FOR PRODUCING ISOXAZOLINE-3-YL-ACYL BENZENE | BASF AKTIENGESELLSCHAFT (DE) | 2001-02-28 | — | — | EP | disclosed |
| WO-2000029394-A1 | METHOD AND NOVEL INTERMEDIATE PRODUCTS FOR PRODUCING ISOXAZOLIN-3-YL-ACYLBENZENES | BASF AKTIENGESELLSCHAFT (DE) | 2000-05-25 | — | — | WO | disclosed |
| WO-1999058509-A1 | METHOD FOR PRODUCING ISOXAZOLINE-3-YL-ACYL BENZENE | BASF AKTIENGESELLSCHAFT (DE) | 1999-11-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020156290-A1 | Herbicides | CBR3, CBR1, SULT1E1 | LMNA 4368/4885EDNRA 4521/4885EDNRB 3751/4885 |
| US-20110152535-A1 | PREPARATION OF ISOXAZOLIN-3-YLACYLBENZENES | CBR3, CYP4X1, UQCRB | LMNA 2052/4885EDNRA 4364/4885EDNRB 3590/4885 |
| US-20030229232-A1 | Herbicides | CBR3, CBR1, SULT1E1 | LMNA 4384/4885EDNRA 4531/4885EDNRB 3761/4885 |
| US-20030018200-A1 | Preparation of isoxazolin-3-ylacylbenzenes | CYP2F1, UQCRB, CYP1B1 | LMNA 2236/4885EDNRA 4612/4885EDNRB 4227/4885 |
| US-20030028033-A1 | Process and novel intermediates for preparing isoxazolin-3-ylacyl benzenes | CYP2F1, CBR3, CBR1 | LMNA 3033/4885EDNRA 4768/4885EDNRB 4755/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.