Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.30 |
| ▸ | CDK1 | P06493 | 1/20 | 0.30 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.30 |
| ▸ | GSK3A | P49840 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4395953 | 0.70 | GSK3B (0.51) | MAPTNPSR1CCNB2CDK1CCNB1 | |
| SCHEMBL7151125 | 0.68 | CYP2D6 (0.38) | MAPTNPSR1CCNB2CDK1CCNB1 | |
| SCHEMBL5101039 | 0.63 | GSK3B (0.44) | NPSR1CCNB2CDK1CCNB1GSK3A | |
| SCHEMBL4393950 | 0.60 | GSK3B (0.50) | MAPTNPSR1CCNB2CDK1CCNB1 | |
| SCHEMBL4992908 | 0.60 | GSK3B (0.53) | MAPTNPSR1CCNB2CDK1CCNB1 | |
| SCHEMBL2909547 | 0.59 | GSK3B (0.37) | CCNB2CDK1CCNB1GSK3AGSK3B | |
| SCHEMBL27559726 | 0.59 | GSK3B (0.39) | CCNB2CDK1CCNB1GSK3AGSK3B | |
| SCHEMBL4395954 | 0.59 | GSK3B (0.69) | CCNB2CDK1CCNB1GSK3AGSK3B | |
| Hydrochloric Acid SCHEMBL2911853 | 0.59 | KAT2B (0.37) | CCNB2CDK1CCNB1GSK3AGSK3B | |
| SCHEMBL14340675 | 0.59 | ASIC3 (0.68) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1317433-A2 | INHIBITORS OF GLYCOGEN SYNTHASE KINASE 3 | CHIRON CORPORATION (US) | 2003-06-11 | — | — | EP | disclosed |
| WO-2002020495-A2 | INHIBITORS OF GLYCOGEN SYNTHASE KINASE 3 | CHIRON CORPORATION (US) | 2002-03-14 | — | — | WO | disclosed |