Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | DPP4 | P27487 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7648977 | 0.82 | GAA (0.47) | ALDH1A1MAPTKDM4ENPC1RAB9A | |
| Formanilide SCHEMBL29177030 | 0.77 | ALDH1A1 (1.00) | ALDH1A1HSP90AA1HSP90AB1SMN1; SMN2NPC1 | |
| SCHEMBL23353504 | 0.77 | ALDH1A1 (1.00) | ALDH1A1HSP90AA1HSP90AB1SMN1; SMN2NPC1 | |
| Formanilide SCHEMBL2463 | 0.77 | — | — | |
| SCHEMBL7029152 | 0.76 | NPC1 (0.39) | ALDH1A1MAPTKDM4ENPC1RAB9A | |
| Formanilide SCHEMBL2543681 | 0.74 | ALDH1A1 (0.94) | ALDH1A1HSP90AA1HSP90AB1SMN1; SMN2NPC1 | |
| Formanilide SCHEMBL10608400 | 0.74 | ALDH1A1 (0.94) | ALDH1A1HSP90AA1HSP90AB1SMN1; SMN2NPC1 | |
| Formanilide SCHEMBL11419741 | 0.74 | ALDH1A1 (0.94) | ALDH1A1HSP90AA1HSP90AB1SMN1; SMN2NPC1 | |
| Formanilide SCHEMBL11116637 | 0.74 | ALDH1A1 (0.94) | ALDH1A1HSP90AA1HSP90AB1SMN1; SMN2NPC1 | |
| Formanilide SCHEMBL569206 | 0.74 | ALDH1A1 (0.94) | ALDH1A1HSP90AA1HSP90AB1SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002041871-A9 | COMPOSITION COMPRISING AN IMEXON OR DERIVATIVES THEREOF AND LIPIDS | UNIV TEXAS (US) | 2003-05-30 | — | — | WO | disclosed |
| WO-2002041871-A2 | COMPOSITION COMPRISING AN IMEXON OR DERIVATIVES THEREOF AND LIPIDS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2002-05-30 | — | — | WO | disclosed |